Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Summer Pharm - Exam 2 > Pain Overview > Flashcards

Pain Overview Flashcards

1
Q

acute pain scale 1-3 =

A

mild

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

acute pain scale 4-6 =

A

moderate → moaning/restless

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

acute pain scale 7-10 =

A

severe → crying out

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

tx for acute mild pain (1-3)

A

NSAIDs

APAP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

tx for acute moderate pain

A

opioids w. slow titration

NSAIDs

+/- adjuvant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

tx for acute severe pain

A

short acting opioids w. rapid titration

NSAIDs

+/- adjuvants

multimodal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

pain = __

+ __

A

perception + reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

acute pain is primarily __

A

nociceptive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

5 common causes of acute pain

A

surgery

acute illness

trauma

labor pain

medical procedures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

2 types of acute/nociceptive pain

A

somatic

visceral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

throbbing, well localized pain

A

somatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

referred pain

A

visceral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

3 benefits of multimodal analgesia/synergism

A

lower doses

opioid sparing

limits s.e

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

3 non opioid analgesic classes

A

NSAIDs

COX-2 selective

APAP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

non-opioid analgesics are commonly used for (4)

A

analgesia

inflammation

antipyretic

antiplatelet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

which non opioid analgesic does NOT help w. inflammation

A

APAP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what non opioid analgesic is commonly used for antipyretic and antiplatelet effects

A

ASA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

4 indications for opioids

A

“nope” →

neuropathy → acute and chronic ca

oa → unresponsive to non opioids

post herpetic/dm neuropathy → unresponsive to non opioids

episodic exacerbations of severe pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

3 synthetic opioids

A

fetanyl

methadone

heroin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

2 natural opioids

A

hydrocodone

oxycodone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

deaths from opioids low to high

A

“methadone helps heal fentanyl”

methadone

heroin

hydro/oxycodone

fetanyl

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

how do local anesthetics produce analgesia

A

block all sensory pain afferent neurons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

LA are commonly used for

A

minor surgical procedures

commonly used w. epi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

6 classes of adjuvant therapy

A

“adolescent alice learned abc”

anticonvulsants

antidepressants

local anesthetics

antispasmodics

benzos

corticosteroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
which 3 adjuvant analgesics are used for neuropathic pain
anticonvulsants antidepressants local anesthetics
26
which adjuvant analgesic is used for anxiety
benzos
27
3 types of chronic pain by duration
neruopathic functional nociceptive
28
chronic pain that persists beyond the normal healing time for an acute injury
neuropathic
29
pain w.o identifiable organic cause abnormal operation of nervous system
functional
30
chronic pain related to chronic dz ex ca or OA
nociceptive
31
2 ex of functional pain
fibromyalgia IBS
32
exaggerated response to normal pain stimuli
hyperalgesia
33
painful response to normal nonnoxioius stimuli
allodynia
34
3 targets of pain sensation/drug therapy
brain → descending inhibition peripheral central
35
2 brain receptors associated w. descending inhibition
NE/serotonin opioid receptors
36
pathways associagted w. peripheral pain inhibition (2)
VSSC prostaglandins
37
pathways associated w. central pain inhibition (3)
VSCC NMDA receptors prostaglandins
38
what 4 drugs target descending inhibition
SNRIs TCADs tramadol opioids
39
what 2 drugs inhibit peripheral sensitization to pain
lidocaine → VSSC NSAIDs → PG
40
what 4 drugs inhibit central sensitization
gabapentin/pregabalin → VSCC ketamine → NMDA NSAIDs/APAP → PG
41
what substance enhances both peripheral and central pain inhibition
PG
42
what 2 drugs activate opioid receptors in the descending inhibitory pathway
opioid analgesics tramadol
43
what 2 drugs block NE-5HT reuptake in the descending inhibitory pathway
antidepressants -\> TCAD SNRI *NOT SSRIs*
44
what drug blocks VSCC → decreases NT release
anticonvulsants
45
what drug blocks NMDA-Glu receptors
ketamine
46
what 3 drugs block COX2
NSAIDs celecoxib APAP
47
what drug blocks VSSC
lidocaine
48
what comorbidity is commonly associated w. chronic pain
dpn
49
what 2 classes of drugs are emphasized in chronic pain
non opioid analgesics adjuvants
50
best drugs for mild to moderate somatic pain
non opioid analgesics
51
4 common indications for non opioid analgesics
**lbp → soft tissue injury** strains/sprains HA **OA/RA**
52
pharm if pain is localized to specific joints
topical NSAIDs
53
3 benefits of adjuvant analgesics
**enhance** analgesic efficacy **treat** concurrent sx exacerbating pain **provide** independent analgesic activity
54
2 ex of TCAD/secondary amine
nortriptyline desipramine
55
4 indications for TCADs as adjuvant
DM neuropathy postherpetic neuralgia lbp migraine
56
4 ex of SNRIs
duloxetine venlafaxine milnaciprain (savella)
57
indication for SNRI as adjuvant analgesic
fibromyalgia
58
3 ex of SSRIs
proxetine fluoxetine sertraline
59
t/f: SSRIs are less effective as adjuvant analgesic than TCADs and SNRIs
T!
60
what does a2o ligand make you think of
anticonvulsants
61
2 ex of anticonvulsants
pregablin gabapentin
62
4 indications for anticonvulsants as adjuvant analgesics
trigeminal neuralgia DM neuropathy postherpetic neuropathy spinal cord injury
63
pharm if pain is localized to specific anatomic area
lidocaine
64
\_\_\_ are less effective for chronic pain and have no long term benefit
opioids
65
t/f: recovery from chronic pain is 4x less likely in pt taking opioids
T!
66
opioids should be reserved for __ pain that adversely affects \_\_
mod-severe ADLs/QOL
67
opioids are controlled substances classified as
C II-III
68
mainstays of tx for neuropathic pain syndromes
antidepressants anticonvulsants/antiepileptics

Summer Pharm - Exam 2 (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions