Pain and thermal sensation Flashcards
What is the difference between Nociceptive pain and neuropathic pain?
Nociceptive:
- stimulation of nociceptors
- Real pain
Neuropathic:
- Abnormal stim, bypasses nociceptor
- Damage to peripheral nerve or CNS
What is the difference between Nociceptive pain and neuropathic pain?
Nociceptive:
- stimulation of nociceptors
- Real pain
Neuropathic:
- Abnormal stim, bypasses nociceptor
- Damage to peripheral nerve or CNS
What is hyperalgesia?
When a painful stimulus causes the perception of more pain than it should.
What effect does substance P have on Mast-cells?
-causes them to degranulate
–>inflammation and more stimulation of nociceptors
What effect does local inflammation have on local anesthetic?
- makes it not work
- pH is low, anesthetics don’t work
- vasodilation allows anesthetic to wash away quickly
What is referred pain?
-The localization of visceral pain is to the region of the same-level somatic innervation
What is referred pain?
-The localization of visceral pain is to the region of the same-level somatic innervation
What receptor does ketamine block? What is the result?
- NMDA
- analgesia
What receptor does ketamine block? What is the result?
- NMDA
- analgesia
What is Allodynia?
-an innocuous stimulus perceived as noxious
What is Allodynia?
-an innocuous stimulus perceived as noxious
what is paracetamol?
acetaminophen
what is paracetamol?
acetaminophen
What is PCA?
- patient-controlled analgesia
- usually morphine
- good b/c pt’s feel like they are in control of their pain
What is PCA?
- patient-controlled analgesia
- usually morphine
- good b/c pt’s feel like they are in control of their pain
