Paget's

Question 1

Symptoms of Paget’s

Answer 1

deafness
heart failure
lytic and sclerotic lesions
increased ALP
(locomotor and hearing loss)
bony pain
warmth over bones and bony deformity 
bowing of legs
enlargement of skull
"increased hat size"

disorder of bone formation and break down.

Question 2

complications of Paget’s

Answer 2

osteoarthritis
nerve compression (VIII- deafness)
fracture
high output cardiac failure (increased turnover)
osteosarcoma

Question 3

Paget’s tx

Answer 3

IV pamidronate (1st dose)
can get reactions like flu=like symptoms, transient pyrexia