Pages 31-40 Flashcards
Abx for perforated viscous?
- Ciprofloxacin
- Metronidazole
- Piperacillin/tazobactam
- Imipenem
What to consider in female patients presenting to ED with syncope or unexplained hypotension?
Ectopic
Sign of IUP on US?
Double decidual sac sign occurring at ~ 4.5-5 weeks after LMP
Rate at which BhCG increases?
Produced by trophoblasts that doubles approximately every 48-72 hours in the first trimester
What what HCG should IUP be visualized?
1500-2000 mIU/mL
How is alloimmunization prevented in expected ectopic?
50 mg RhoGAM
Rx mgmt ectopic? MOA? Success rate?
Methotrexate
- Interferes w/ syntheses of DNA and cell replication of fetal cells, resulting in involution of the pregnancy
- Failure w/ single dose methotrexate occurs in up to 36% of patients necessitating second dose
Side effects methotrexate?
- Abdominal pain 3-7 days after administration secondary to tubal abortion or expanding hematoma within the fallopian tube
- Worsening pain need be evaluated for tubal rupture, and the need for immediate rescue laparoscopy
What is purulent cervical discharge indicative of?
PID
Rx PID Inpatient?
- Cefoxitin 2 g q6 IV + Doxycycline 100 mg PO
OR
2 Cefotetan 2 g q 12 IV + Doxycycline
O/P treatment PID?
- Ceftriaxone 250 mg IM
OR - Cefoxitin 2 grams IM + Probenecid 1 gram PO
OR
AND
Doxycycline 100 mg BID for 14 days
- Addition of Metronidazole 500 mg BID for 14 days should be considered
What is cremasteric reflex and what does it indicate?
Loss of cremasteric reflex is most accurate sign of testicular torsion
- Elicited by stroking ipsilateral thigh which leads to reflex elevation of ipsilateral testicle by greater than 0.5cm
In which type of shock does HR go down?
None
When does CVP go up in shock?
- Cardiogenic
2. Obstructive
When does CVP go down in shock?
- Hypovolemic
2. Distributive
Types of distributive shock?
- Septic
- Neurogenic
- Anaphylactic
When does contractility increase in shock?
Hypovolemic
When does contractility decrease in shock?
Cardiogenic
When does SVR increase in shock?
- Cardiogenic
- Tamponade
- PE
- Hypovolemic
When does SVR decrease in shock?
- Tension pneumothorax
2. Distributive
Define anaphylaxis?
Acute onset illness w/ involvement of: 1. Skin: hives, pruritus or 2. Mucosal tissue: swollen lips/tongue AND either 1. Respiratory compromise OR 2. Reduced BP (<90 Sys or > 30% dec) - or associated symptoms of end-organ dysfxn
Anaphylaxis rx and dosing?
- STOP EXPOSURE
- EPI in anterolateral thigh (1:1000=IM or 1:10000 IV).
- Adults: .3-.5 mg every 5-10 minutes
- Kids: .01mg/kg up to .3mg q 5-10 minutes.
Fluids in anaphylaxis?
1L NS bolus over 5-10 minutes, can need up to 5-7L in severe cases
Secondary Rx anaphylaxis?
- H1 blockers: Diphenhydramine 50mg IV
- Steroids: DEXAMETHASONE 10mg IV
or
2.a Methylprednisolone 125mg IV) - O2
- Glucagon
What is the SIRS criteria?
2 of the following:
- Temperature less than 36or greater than 38
- HR greater than 90 BPM
- RR > 24 breaths per minute or PaCO2 < 32
- WBC less than 4,000 or greater than 12,000
Definition of sepsis?
SIRS plus presence of infection
What is severe sepsis?
Sepsis plus evidence of organ failure or lactate > 4
Examples of end organ failure?
- CNSL Delirium
- Pulmonary: ALI/ARD
- Thrombocytopenia
- Liver: Hyperbilirubinemia
- Acute renal failure
- Lactate more than 4
Definition septic shock?
Sepsis plus hypotension unresponsive to 2 fluid boluses of 20-30 cc/kg
- Hypotension defined as a systolic less than 90 or 40 below baseline BP
Tests for sepsis at Loyola?
- WBC
- Lactate
- Procalcitonin
- Cultures
- Radiographs
- ABG
- Platelets
- LFTs
- BUN/creatinine
What does lactate represent?
Global HYPOperfusion
When is procalcitonin elevated?
Systemic bacterial / fungal infections, NOT viral
Central venous O2 sat goal in sepsis?
ScvO2 greater than 70mm Hg