Pages 31-40 Flashcards
Abx for perforated viscous?
- Ciprofloxacin
- Metronidazole
- Piperacillin/tazobactam
- Imipenem
What to consider in female patients presenting to ED with syncope or unexplained hypotension?
Ectopic
Sign of IUP on US?
Double decidual sac sign occurring at ~ 4.5-5 weeks after LMP
Rate at which BhCG increases?
Produced by trophoblasts that doubles approximately every 48-72 hours in the first trimester
What what HCG should IUP be visualized?
1500-2000 mIU/mL
How is alloimmunization prevented in expected ectopic?
50 mg RhoGAM
Rx mgmt ectopic? MOA? Success rate?
Methotrexate
- Interferes w/ syntheses of DNA and cell replication of fetal cells, resulting in involution of the pregnancy
- Failure w/ single dose methotrexate occurs in up to 36% of patients necessitating second dose
Side effects methotrexate?
- Abdominal pain 3-7 days after administration secondary to tubal abortion or expanding hematoma within the fallopian tube
- Worsening pain need be evaluated for tubal rupture, and the need for immediate rescue laparoscopy
What is purulent cervical discharge indicative of?
PID
Rx PID Inpatient?
- Cefoxitin 2 g q6 IV + Doxycycline 100 mg PO
OR
2 Cefotetan 2 g q 12 IV + Doxycycline
O/P treatment PID?
- Ceftriaxone 250 mg IM
OR - Cefoxitin 2 grams IM + Probenecid 1 gram PO
OR
AND
Doxycycline 100 mg BID for 14 days
- Addition of Metronidazole 500 mg BID for 14 days should be considered
What is cremasteric reflex and what does it indicate?
Loss of cremasteric reflex is most accurate sign of testicular torsion
- Elicited by stroking ipsilateral thigh which leads to reflex elevation of ipsilateral testicle by greater than 0.5cm
In which type of shock does HR go down?
None
When does CVP go up in shock?
- Cardiogenic
2. Obstructive
When does CVP go down in shock?
- Hypovolemic
2. Distributive
Types of distributive shock?
- Septic
- Neurogenic
- Anaphylactic
When does contractility increase in shock?
Hypovolemic
When does contractility decrease in shock?
Cardiogenic
When does SVR increase in shock?
- Cardiogenic
- Tamponade
- PE
- Hypovolemic
When does SVR decrease in shock?
- Tension pneumothorax
2. Distributive
Define anaphylaxis?
Acute onset illness w/ involvement of: 1. Skin: hives, pruritus or 2. Mucosal tissue: swollen lips/tongue AND either 1. Respiratory compromise OR 2. Reduced BP (<90 Sys or > 30% dec) - or associated symptoms of end-organ dysfxn
Anaphylaxis rx and dosing?
- STOP EXPOSURE
- EPI in anterolateral thigh (1:1000=IM or 1:10000 IV).
- Adults: .3-.5 mg every 5-10 minutes
- Kids: .01mg/kg up to .3mg q 5-10 minutes.
Fluids in anaphylaxis?
1L NS bolus over 5-10 minutes, can need up to 5-7L in severe cases
Secondary Rx anaphylaxis?
- H1 blockers: Diphenhydramine 50mg IV
- Steroids: DEXAMETHASONE 10mg IV
or
2.a Methylprednisolone 125mg IV) - O2
- Glucagon
What is the SIRS criteria?
2 of the following:
- Temperature less than 36or greater than 38
- HR greater than 90 BPM
- RR > 24 breaths per minute or PaCO2 < 32
- WBC less than 4,000 or greater than 12,000
Definition of sepsis?
SIRS plus presence of infection
What is severe sepsis?
Sepsis plus evidence of organ failure or lactate > 4
Examples of end organ failure?
- CNSL Delirium
- Pulmonary: ALI/ARD
- Thrombocytopenia
- Liver: Hyperbilirubinemia
- Acute renal failure
- Lactate more than 4
Definition septic shock?
Sepsis plus hypotension unresponsive to 2 fluid boluses of 20-30 cc/kg
- Hypotension defined as a systolic less than 90 or 40 below baseline BP
Tests for sepsis at Loyola?
- WBC
- Lactate
- Procalcitonin
- Cultures
- Radiographs
- ABG
- Platelets
- LFTs
- BUN/creatinine
What does lactate represent?
Global HYPOperfusion
When is procalcitonin elevated?
Systemic bacterial / fungal infections, NOT viral
Central venous O2 sat goal in sepsis?
ScvO2 greater than 70mm Hg
Afterload goal in sepsis?
Titrate vasopressors to achieve MPA 65 - 90
CVP goal in sepsis
Rapid, early fluid boluses to achieve aCVP 8-12
UO goal in sepsis?
0.5 cc/kg/hour in adults
What to do if ScvO2 is less than 70% in sepsis?
- Hematocrit less than 30%: transfuse PRBC
2. Hematocrit is greater than 30%: dobutamine
When do abx need to be given in sepsis?
Within 3 hours of arrival
How to confirm proper ET tube placement?
End-tidal CO2 is most accurate technology
Compression to ventilation ratio w/o secured airway?
30 Compression : 2 breaths
Ventilation rate in a patient 2/ ongoing CPR and advanced airway?
1 Ventilation every 5-6 seconds (8-10/minute)
Rhythms requiring defibrillation?
Vfib or Vtach WITHOUT PULSE
Where to place need in tension pneumo?
14-16 gauge long angiocath in midclavicular line at 2nd intercostal, over rib to avoid NV bundle
Ddx pulseless electrical activity?
- Tension Pneumo
- HYPERkalemia
- HYPOglycemia
What to do if TACHY causes HYPOtension, AMS, signs of shock, ischemic chest pain, or acute HF?
Synchronized cardioversion!!!
- 100J if regular Narrow or wide
- 200J mono/biphasic if narrow irregular
Management narrow QRS v-tach?
- Vagal maneuvers,
- Consider Adenosine IF REGULAR
- BB and CCBs
Management Vtach with QRS greater than .12?
- Adenosine IF regular and monomorphic
Otherwise - Amiodarone 150mg over 10 minutes followed by 1mg/min for 1st 6 hours
Meds used in cardiac arrest?
- 1mg EPI every 3-5 minutes IV/IO
- Vasopressin 40U IV/IO can replace 1st or 2nd dose of EPI
- Amiodarone 300mg bolus IV/IO ONLY for V-FIB/VTACH, second dose is 150mg bolus.
Whats does palpable radial pulses suggest?
Systolic blood pressure of at least 80
What does palpable femoral and carotid but no radial suggest?
Systolic of at least 60
Most common cause preventable death in kids?
Failure to control airway
What is Cardiopulmonary Failure?
When Resp Failure (AMS) + Shock Leads directly to Cardiopulmonary arrest
Only type SHOCK IS ONLY TYPE OF SHOCK THAT WORSENS WITH FLUID BOLUSES?
CARDIOGENIC
Difference between respiratory distress and failure?
DISTRESS:=increased WOB
FAILURE= AMS from inadequate oxygenation or ventilation
In kids does BP assess volume well in early schok?
No
Definition HYPOtension in kids based on age?
- 0-1mo: 60
- 1mo-1yr: 70
- 1yr-10yr (70 +(2*age)) >
- 10 yrs =90mmHg
Verbal GCS scale in infants?
- Coos: 5
- Irritable cries: 4
- Cries to pain: 3
- Moans to pain:
- Nothing: 1
Most common cause bradycardia in kids?
Hypoxia
Urine output consideration in young kids?
Less than 2 yrs cannot concentrate urine
- NORMAL=1-2cc/h
What is special about catecholamines?
They are catecholamine deplete: don’t use Vasopressin or Dopamine
**Better EPI and NE, Dobutamine and Milrinone
What does PGE1 do?
PGE1 MAINTAINS PATENCY OF DUCTUS: can cause resp depression so READY TO INTUBATE
What to do in kids with anaphylaxis?
Use both H1 and H2 blockers
How to give fluids in hypovolemic shock in kids?
- 20cc/Kg bolus: always NS/LR
2. After 3 Crystalloid GIVE 1 COLLOID
FiO2 management in kids in schock?
Ttrate to Sats over 94% BUT under 100% to prevent hyperoxia
First sign shock in kids?
Tachycardia
- Hypotension = decompensation in kids
What is otalgia?
Pain in ear
Ddx otalgia?
- External otitis
- Otitis media
- Mastoiditis,
- Auricular infections.
- TMJ
- Neoplasm
- Dental problems
- Tonsillitis
- Laryngitis
- Sinusitis
What is odynophagia?
Painful swallowing
Most common cause OM?
- S.pneumo
- Hflu
- RSV
Presentation mastoiditis?
Purulent otorrhea and tenderness over mastoid
Rx OM?
Cipro/Dexamethasone
Diagnosis Peritonsillar abscess?
Needle aspiration, CT or US
Most common cause Retropharyngeal abscess?
GABHS
When is thumbprint sign seen?
Eppiglotitis
Rx epiglottitis?
- Humidified O2
2. Cephalosporins
What is Ludwig’s Angina? Cellulitis of submandibular and lingual space→spread of odontogenic infection (2nd/3rd molars
Cellulitis of submandibular and lingual space from spread of odontogenic infection in 2nd/3rd molars with get dysphagia, trismus, edema of floor of mouth
Rx Ludwig’s angina?
Early decadron and Abx
What is CENTOR Criteria?
Criteria for pharyngitis CERVICAL LAD NO cough TONSILLAR EXUDATE TENDER NO cough Hx of FEVER 0-1: NO test no tx 2-3 rapid strep 4 empiric Abx
Rx pharyngitis?
IM benzathine penicillin or Pen-VK po
Rx epistaxis?
- Pinch x20 minutes
- Vasoconstrictor soaked Q-tips x 10 minutes
- Cauterize w/Silver nitrate
- Pack, then prophylactic CEPHALEXIN
What is DKA?
State of absolute insulin deficiency, hyperglycemia, anion gap acidosis, and dehydration seen in Type 1 diabetics
Causes DKA?
- Infections
- Disruption of insulin therapy
- Presentation of new onset diabetes
What is HHS?
“Hyperosmolar Hyperglycemic State”
- Seen in type II diabetics
What are Kussmaul respirations?
Fast and deep breaths seen in DKA