Pages 11-20 Flashcards
Critical decisions and interventions in pneumonia?
- Appropriate room w/ standard and droplet precautions.
- Full set of vital signs w/ pulse ox
- Supplemental oxygen for hypoxic patients.
- Evaluate mental status and ability to protect airway
- If hypotensive: 2 IVs should be established
- Normal saline or lactated ringers
- Should hypotension not respond to fluids, pressors - Antibiotics once diagnosis made
- Early administration improves outcomes - IVF
- O2
Diagnostic testing for pneumonia?
- CXR: may not show early in illness
- If H/P strongly suggest, absence of infiltrate doesn’t prevent the diagnosis and treatment. - ABG: not needed for most patients
- Useful when considering intubation - Sputum evaluation: sensitivity is around 50%
What can lateral CXR show in pneumonia?
Infiltrate in a retrocardiac location
When are Lobar infiltrates seen?
Bacterial infections
When are Interstitial patterns seen?
Pneumocystis carinii and Mycoplasma
When are Cavitary lesions seen?
TB or fungal infection
When are Pulmonary abscesses seen?
Staphylococcus or Klebsiella
Bad prognostic signs for pneumonia in ABG?
Respiratory acidosis with elevation of pCO2 worrisome for impending respiratory failure
Sign of good sputum sample in pnuemonia
Less than 10 squamous cells per HPF and greater than 25 WBC per HPF
Abx for CAP?
- Doxycycline
- Macrolides
- Sulfonamides
- Fluoroquinolones
Abx for Aspiration pneumonia?
- Ampicillin/sulbactam
- Piperacillin/tazobactam
- Clindamycin + aminoglycoside
Abx for Nosocomial pnuemonia?
- Antipseudomonal B-Lactam Plus:
a. Piperacillin/ tazobactam
b. Imipenem
c. Meropenem
d. Cefepime or Ceftazidime - Anti-MRSA agent:
a. Vancomycin
b. Linezolid
Abx for pneumonia in kids?
- Amoxicillin
2. Macrolides
Curb 65 Criteria?
One point for each:
- Confusion
- Urea greater than 19
- Respiratory rate over 30
- SBP under 90 or DBP under 60
- Age over 65
Curb 65 recs?
0-1: Treat as an outpatient
2-3: short stay or watch as outpatient
4-5: Hospitalization, maybe ICU
When do asthmatics need rapid tube intubation?
Severe respiratory distress AND one of the following:
- Albuterol or other therapies do not reverse symptoms
- Significant hypoxia even with O2
- Too tired to breathe on own
How often do asthmatics need airway management?
Acute asthma requires airway management in less than 1% of patients
How is O2 administered in acute asthma?
Usually administered w/ aerosolized B2-adrenergic bronchodilator at 6-8 L / min in a nasal cannula (mild exacerbations) or a non-rebreather (severe exacerbations)
Goal of O2 therapy in acute asthma?
SpO2 more than 92%
Management severe acute asthma exacerbation that is not improving with aerosolized albuterol?
1a. Subcutaneous epinephrine 0.2 mg
or
1b. Terbutaline 0.25 mg
2. Corticosteroids oral or IV: onset 4-6 hours
Negative side effects of epinephrine?
B1 and a-effects which can lead to tachycardia or myocardial ischemia
What is the best predictor of result in acute asthma exacerbation?
Results at 1 hour after initiation of treatment of PFTs and peak flow
How often can nebulized albuterol be used?
Every 20 minutes for up to 3 dose
- Higher doses of a continuous albuterol via a nebulizer is not necessarily more effective than repeated lower doses, but is frequently used in patients with severe exacerbations or when the patient does not respond to the initial 3 doses
What is Ipratropium and when is it used? Best route?
Anticholinergic agent used in severe asthma or Beta-blocker induced asthma
- There is evidence that combining it with a β2-adrenergic agonists may provide additional benefit compared to a β2-adrenergic agonists alone
- IM faster and more consistent delivery than SC
Can theophylline be used in acute asthma exacerbation?
Not recommended in acute asthma
Is there evidence for use of Non-invasive positive pressure ventilation (NPPV) in acute asthma?
- Provides inspiratory assistance as well as PEEP
- Enhances patient breathing in acute respiratory conditions by providing rest in patients w/ significant work of breathing and early fatigue
- Use in COPD and CHF patients has been well established
- Use in acute asthma has been studied and is promising, but needs further evidence
Goal before discharge in acute asthmatic?
To obtain more than 70 percent predicted or personal best FEV1 or PEFR
Describe the treatment of COPD exacerbation?
- Oxygen: to all hypoxic patients w/ suspected COPD
- Use Venturi mask NC
- Avoid use of a non-rebreather mask with 15 L/min of oxygen, unless not responding to lower flow rates
- In patients w/ chronic CO2 retention, may cause respiratory depression w/ the rapid rise in O2 depressing central ventilatory drive
Next step after O2 in COPD exacerbation?
1a. Albuterol : bronchodilators provide most rapid response
- Even after multiple doses a response may occur
- No role for long acting B-agonists (salmeterol)
or
1b) Ipratropium bromide: given every 4 hours
- Combination therapy is not superior
Use of steroids in COPD exacerbation? Difference in treatment course from asthma?
- IV steroid such as methylprednisolone or prednisone orally should be started in the ED to help treat inflammatory component
- Typical regimens are 10-14 days with tapering doses in contrast to 5 day pulse therapy w/ asthma