Page 4 Flashcards
The degradation product of hemoglobin in the reticuloendothelial
system.
Bilirubin
Hemoglobin breakdown components?
Iron, protein, protoporphyrin
What cell converts protoporphyrin into bilirubin?
ReticuloEndothelial cells
Biliburin is transported via?
Conjugation
Conjugated bilirubin passes from what to where before converting to urobilinogen?
Bile canaliculi, to duodenum
Bilirubin in urine means what?
Liver damage
Bilirubinuria can detect these diseases
Hepatitis
Cirrhosis
Gallbladder Dse
Cancer
Reaction for bilirubin test?
Diazo reaction
Oxidation test
Reagent strip reagents for bilirubin?
2,4-dichloroaniline diazonium salt
OR
2,6-dichlorobenzene diazonium
+
2,4-dichloroaniline diazonium salt
OR
2,6-dichlorobenzene diazonium-tetraflouborate
Bilirubin reagent strip color range
Tan/Pink to Violet
Bilirubin confirmatory test/verification test if questionable
Ictotest
Ictotest Reaction
Diazo reaction
Ictotest form and reagents
Tablet form
: p-toluenesulfonate
: sulfosalicylic acid
: sodium carbonate
: boric acid.
Ictotest color reaction?
Blue to purple
Oxidation reagent composition
FeCl in TCA/Fouchet’s reagent