Paeds - Respiratory Flashcards
How do URT disorders present?
Coryza, sore throat, earache, sinusitis, stridor
How do LRT disorders present?
Cough, wheeze, resp distress
What % children after affected by asthma?
1/10
What is asthma?
Chronic airway inflammation + bronchial hyperactivity, reversible airway obstruction
What are the 2 patterns of wheezing in asthma?
Viral induced wheezing
Multiple trigger wheeze
What are the risk factors for viral induced wheezing?
Maternal smoking
What is not a risk factor fr viral induced wheezing?
FHx of asthma
At what age does viral induced wheezing resolve by?
Aged 5
What conditions is multiple trigger wheeze associated with?
Eczema
Rhinosinusitis
What is the pathological triad in asthma?
B inflamm
Hyper-response
Airway narrow
What is the clinical triad in asthma?
Cough
Wheeze
SOB
O/E - Asthma (5)
Normal between attacks Hyperinflation of chest Barrel-shaped chest Polyphonic expiratory wheeze Harrison sulci
Ix in asthma
Allergies - skin prick/IgE
CXR - rule out pathology
Spirometry - PEFR
E.g. of SABA?
Salbutamol
Is Salbutamol a reliever or preventer?
Preventer
How long does salbutamol work for?
2-4hrs
SE salbutamol?
Tremor
E.g. of LABA
Salmeterol
Is salmeterol a reliever or preventer?
Reliever
How long does salmeterol work for?
12hrs
In what conjunction must salmeterol be used?
W/ an ICS
What specific type of asthma is salmeterol useful in?
Exercise induced asthma
When is Ipratropium used?
In infants
When others = found to be effective
or
Severe acute asthma
E.g.s of ICS
Beclomethasone
Is Beclomethasone a preventer or reliever?
Preventer
How must you take beclomethasone for it to work?
Take daily
SE beclomethasone
Oral candidiasis
High doses - impaired growth, adrenal suppression, altered bone pets
Add on therapies in asthma
LTRA - Montelukast
Theophylline
PO steriods
Omaluzinab
Step by step approach - Asthma, <5 y/o
1) SABA as required
2) + LTRA or ICS (200-400mcg)
3) If on LTRA + ICS, if on ICS + LTRA
4) Rx to consultant
Step by step approach -Asthma >5y/o
1) SABA
2) + ICS (200-400Mcg)
3) + LABA
4) incr dose ICS to 800mcg
5) + PO steroid @ lowest dose + Rx to consultant
What age is a pressurised meter dose inhaler for?
All ages
<2 need face mask + spacer
>2 - spacer alone
What age is a breath inhaler for?
6+
What age is a dry powder inhaler for?
4+
Features of a severe acute asthma attack(6)
Tachypnoea O2 sats <92% PEFR 33-50 Can't talk in full sentences TachyC Signs of resp distress
Features of a life threatening acute asthma attack (5)
Silent chest Decr RR PEFR <33 Decr consciousness/agitation Cyanosis - O2 < 85
When should you admit an asthmatic child to hospital? (3)
Won’t respond to high dose bronchodilator
Marked reduction PEFR
O2 in air <92%
Mx moderate asthma attack (2)
SABA + spacer 2-4 puffs every 2 mins
PO Prednisolone 1-2mg/kg
Mx severe asthma attack (4)
High flow O2
SABA - 10 puffs via spacer
PO Pred/IV Hydrocortisone
Consider - Ipratropium/IV SABA/Mg
Mx life threatening asthma attack (5)
15L High flow O2 SABA PO Prednisolone/IV HC Ipratropium IV SABA or Mg
If child is responding to Tx in an acute asthma attack, what should be done?
Continue bronchodilators every 1-4hrs prn
PO pred for 3 days
If child is not responding to Tx in an acute asthma attack, what should be done?
Transfer to HDU/PICU
Wheeze differentials (8)
Transient early wheeze Non-atopy wheeze (post-viral) Cardiac failure Bronchiolitis Pneumonia CF GOR Croup
What is the most common respiratory infection in infancy?
Bronchiolitis
Which season is Bronchiolitis more common in?
Winter
What is the peak age for bronchiolitis?
3-6months
Which organism causes >80% bronchiolitis?
RSV
Other causative pathogens bronchiolitis (3)
Parainfluenza
Rhinovirus
Adenovirus
RF Bronchiolitis (5)
Older siblings
Nursery
Passive smoke
Pre-term or LBW
Sx Bronchiolitis
Coryzal Sx –> Dry cough + Incr SOB
Inspection findings - Bronchiolitis
Recession
TachyC
Pallor
Percussion findings Bronchiolitis
Hyper-inflated chest
Auscultation findings - Bronchiolitis
Fine end insp crackles
Wheeze - Exp > Insp
Ix bronchiolitis (3)
PCR secretions
O2 sats
Blood gas
Mx bronchiolitis (4)
Supportive
Humidified O2
IV Fl
Highly infective - stop spread
Prognosis bronchiolitis
Most recover 2 w
1/2 have recurrent cough/wheeze
What prevention can be given for bronchiolitis?
Palibuzimab
When should someone with bronchiolitis be admitted to hospital?
If feeding <50% usual
Or Increasing dyspnoea
Causes - newborn pneumonia (2)
GBS
Gram -ve bacilli
Causes - infant pneumonia (4)
RSV
Strep P
H influ
Staph A (serious)
Causes - > 5y/o pneumonia (3)
Mycoplasmum P
Strep P
Chlamydia
Which vaccine has markedly reduced pneumonia incidence?
HiB vaccine
Clinical features pneumonia (6)
URTI followed by: Fever Cough Rapid breathing - most sensitive sign Lethargy Poor feeding Localised chest/neck/pain
Inspection - child w/ pneumonia (4)
Tachpnoea
Nasal flaring
Chest recession
O2 sats
Percussion - child w/ pneumonia
Dull
Auscultation - pneumonia
End insp coarse crackles
Decr sounds
Bronch breathing
Ix - pneumonia (3)
Chest x-ray
N-P aspirate can determine viral/bacterial cultures
Mx - pneumonia - when to admit (5)
O2 <92% Severe tachypnoea Difficulty breathiing Apnoea No feeding
Mx pneumonia in hospital (4)
O2
Analgesia
IV Fl
ABx - neonate/broad spec, infants - amox
What is pertussis
Whooping cough
Causative organism Pertussis
Bordetella pertussis
How often do Pertussis epidemics occur?
Ever 3-4years
Transmission pertussis
droplet spread
Incubation period pertussis
20 days
What is the most infectious phase pertussis?
Catarrhal phase
For how long should someone with pertussis stay away from school?
21 days after Sx
5 days from starting ABx
Catarrhal phase pertussis
1-2 w coryza/runninig nose
paroxysmal phase - up to 3 months (6)
Dry hacking cough Prolonged eps Then whooping cough Worse @ night --> vomiting During child goes red/blue Apnoea
O/E pertussis (2)
Cough
Tired child
Ix pertussis (5)
NOTIFITABLE N-p swabs PO fl testing (>5 y/o) Serology if cough >2w PCR
Mx pertussis (3)
Admit
Abx - infected pt + contacts (clarithromycin)
Prophylaxis
Abx pregnant woman ABx for pertussis
Erythromycin
Sx of 1’ infection TB (3)
Fever
Decr Wt
Cough
Xray appearance 1’ TB
Hilar lymphadenopathy
Collapse/consolidation
Diagnosis TB (4)
Sputum sample
Check urine. LN + CXR
Mantoux
IFN gamma
Tx TB
RIPE
Decreased to R+I - 2 months
Carrier rate CF
1/25
Life expectancy CF
+/- 40years
Which gene is defective in CF?
CFTR gene
What does the severity of CF depend on?
Gene mutation
Microbial pathogens
Passive smoking
Social deprivation
CF - affect on airways (4)
Decr airway liquid layer
Decr ciliary fct
Incr mucopurulent secretion
Dysregulation of inflammation = incr infection rate
CF - affect on abdomen
Thick meconium in intestines –> meconium ileus
Pancreatic ducts blocked –> malabsorption
CF - affect on sweat glands
Incr NaCl in sweat
Clinical features CF (4)
Recurrent chest infections
Poor growth
Malabsorption
Failure to thrive
O/E - CF (4)
Hyper-inflated chest
Coarse inspiratory creps
Expiratory wheeze
Clubbing
Ix CF (3)
Guthrie
Sweat test
Genetic screening
Mx (7)
Measure FEV1 regularly PT b.d Exercise - deep breathing Continuous proph ABx - fluclox IV Abx if Sx Lung transplant Nutritional - ADEK vits, incr kcal
Fertility CF
F - norm
M - almost always infertile
What is epiglottitis
Inflammation epiglottis
Cause epiglottitis
HiB
Age epiglottitis
1-6 years old
S+S epiglottitis (6)
High fever Painful throat Saliva drools Soft insp stridor Minimal cough Swollen epiglottis
Mx epiglottitis (6)
Admit Transfer --> ITU Intubate under controlled conditions Bloods - culture IV Abx Prophylactic Hib - contacts
Recovery time epiglottitis
2-3 days
Why are children prone to OM?
B/c have short, horizontal eustachian tubes
RF AOM (6)
FH Cleft palate ET abnormalities Downs Immunocompromised Smoke exposure
S+S AOM (3)
Otalgia
Fever
TM - bright red + bulging
Common pathogens AOM (5)
RSV Rhinovirus Pneumococcus H.influenza Morazella catarrhalis
Tx AOM
Analgesia
Most resolve spontaneously
Which Abx should you give for AOM if it is not resolving?
Amoxicillin
Complications AOM (2)
Mastoiditis
Meningitis
S+S Glue ear (3)
CHL
Otherwise asymp
TM dull + retracted + fl level
What is the most common cause of Conductive hearing loss in children
Glue ear
Adenoidectomy indications
Recurrent OME + hearing loss
OSA
Tx tonsillitis (3)
Pen/erythro 10 days
iif severe - admit + IV fl + analgesia
Tonsillectomy
Indications tonsillectomy (3)
Recurrent - 1/7, 2/5, 3/3
Quinsy
OSA
What is a Coryza
Common cold
Causes coryza (2)
RSV
Rhinovirus
PS Coryza (3)
Clear/mucopurulent rhinorrhoea
Nasal obstruction
Cough - up to 4 w after
Tx Coryza
Ibu + paracetamol
Why is frontal sinusitis unlikely in a child?
Because frontal sinus doesn’t develop until >10 years old
Tx sinusitis (3)
ABx
Analgesia
TO decongestants
Define fever
> 38
Measuring temperature in a child <4 months
Electronic thermometer axilla
Measuring temperature in a child >4 months
Axilla or infra=red tympanic thermometer
Infective causes of fever (7)
Localised infection - meningitis/pneumonia/UTI Bacterial infection Deep abscess Infective endocarditis TB Viral infection Parasitic infection
Non-infective causes of fever
Systemic juvenile idiopathic arthritis SLE Vasculitis IBD Malignancy Sarcoidosis
A fever is more significant if: (6)
>41' Bacterial sepsis SCA Suppressed immunity Congen heart disease Severe head injury
Signs of a fever indicating serious illness (7)
Low level consciousness Weak/high-pitched/continuous cry Pale/mottled/blue skin Reduced skin turgor Signs resp distress Bulging fontanelle
Mx fever (6)
Tx underlying cause Antipyretics - P +I Place in cool room Open window/use fan Reduce amount clothing/bedding Keep infants head uncovered
At what age do feibrile convulsions send to occur?
6m - 5y/o
How long do febrile convulsions occur for?
<2 mins
Features of a simple febrile convulsion (3)
Isolate
Generalised
T-C seizures
Features complex febrile consulsion
One or more of: Focal onset >15mins Recurs within 24hrs/w/ same febrile illness Incomplete recovery within 1hr
Febrile status epilepticus
Lasts >30mins
If a seizure lasts > 5mins, what should be done?
Rectal Diazepam
or
Buccal midazolam
Peak age Croup
2
Which season is Croup most common in?
Autumn
Causes of Croup (2)
Parainfluenza
RSV
Sx Croup (7)
Coryza Fever Hoarseness BARKING cough Harsh stridor SOB (worse @ night)
Mx Croup - mild
Mx at home
Watch closely for worsening signs
Mx Croup - mod
Inhal moist air
PO Dex/pred/neb steroids
Mx Croup - severe
Neb’ adrenaline + O2
Sx bacterial tracheitis
Croup + Fever Toxic Rapidly progressive airway obstruction Thick secretions
Cause bacterial tracheitis
Staph A
Mx Bacterial Tracheitis
IV ABx + intubate/vent
What is hoarseness
Inflamed vocal cords
What is more fatal, smoke inhalation or burns?
Smoke inhalation
Mx smoke inhalation
Remove from smoke ASAP Airway patency 100% O2 via non-rebreathe Intubate Fl replacement if burns