Paeds - neuro Flashcards

1
Q

Management of Infantile spasms

A

`im ACTH daily/oral red

Vigabatrin if tuberous sclerosis

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2
Q

Ix in child with reflex anoxic seizures

A

ECG

Hb/ferritin

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3
Q

signs of a complex febrile convulsion

A

Focal seizure
>15 mins
>1 episode in a single illness

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4
Q

Advice to parents of febrile convulsion

A

Arrange GP review

  • 1/3 will recur
  • if generalised, no increased risk of epilepsy
  • Avoid head trauma
  • safety net: non-blanching rash, >5 mins, confusion post octal state, fever >5 days, >1 convulsion in same illness
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5
Q

Drug often used for epilepsy patient with generalised seizures

A

sodium valproate

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6
Q

Drug often used for epilepsy patient with focal seizures

A

carbemazepine

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7
Q

When is MRI indicated in ?epilepsy

A

Focal seizures
<2yo
Poor response to drug tx

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8
Q

Bells palsy - which CN?

A

7

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9
Q

Which virus is bells palsy commonly associated with

A

HSV

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10
Q

Complication of bells palsy? why?

A

Conjunctivitis (eye can’t close)

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11
Q

Pathophysiology behind Duchenne MD?

A
  • X-linked recessive

- Dystrophin mutation –> disrupted Ca-calmodulin complex –>myofibre necrosis

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12
Q

Later features of DMD

A

Resp failure
Cardiomyopathy
Wheelchair bound by 10-14yo
Scoliosis

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13
Q

2 useful meds for DMD

A

Predinoslone

VitD and Ca

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14
Q

Becker’s vs duchennes

A

Beckers is a slower progression

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15
Q

Cause of myotonic MD

A

nucleotide triplet repeat expansion

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16
Q

Useful (and unusual) management of HIE

A

Mild hypothermia for 3 days

17
Q

Features of Tuberous sclerosis

A

Leaf like patches
Rough patches
Adenoma sebaceum

West syndrome
Focal seizures

18
Q

Neurofibromatosis

A

> 6 cafe au last spots
Axillary freckling

Lisch nodule
Neurofibroma
Optic gnome

1st degree relative with NF

19
Q

Dilated pupil on R side
History of trauma
CN 6 palsy

A

R sided extradural haemorrhage

20
Q

Ix in suspected NAI –> cerebral haemorrhage

A

CT head
full skeletal survey
Ophthalmoscopy
Coagulation screen

21
Q

Port wine stain - what exactly is it? when should an MRI be done in these patients and why?

A

Hemangioma

  • if it is on the hair line or trigeminal nerve distribution –> risk of epilepsy