Paeds - infection + immunity

Question 1

three complications of VZV infection

Answer 1

2ndary bacterial infection
Encephalitis - esp cerebllitis
Purpura fulminans - from vasculitis in skin + subcut tissues due to cross reactivity of antiviral antibodies with protein S

Question 2

In an otherwise healthy individual, what is the Mx of VZV infection

Answer 2

paracetamol + calamine lotion + antihistamines

Increase fluid intake and avoid immunocomp/pregnant/babies

Question 3

Parvovirus B19 infection in a child - what are the clinical fx

Answer 3

Prodrome –> slapped cheek + lace like rash on limbs

If haemolytic anaemia –> aplastic crisis

Question 4

School exclusion for slapped cheek syndrome

Answer 4

Not necessary as they are no longer infective once symptoms have arisen

Question 5

Mx of measles

Answer 5

Supportive + inform PHE + PEP OF CLOSE CONTACTS

Question 6

Long term complication of measels

Answer 6

Subacute sclerosing panencephalitis