Paediatrics Flashcards
what are the signs of periorbital cellulitis?
acute erythematous swelling of eyelid (unilateral)
what are the signs of orbital cellulitis?
painful eye movements, diplopia, visual disturbance, fever, lid swelling, PAIN, proptosis
how do you investigate a swollen eye?
CT orbit
what are the two types of squint?
esotropia = convergent exotropia = divergent
what are the two tests to diagnose a squint?
- corneal reflection test
2. cover test
how do you manage a squint? (3 Os)
OPTICAL
ORTHOPTIC - patching of eye encourages strengthening
OPERATIONS - botox injection/resection of rectus muscle
what is Hirschprungs disease?
absence of ganglia in the colon segment which leads to a functional GI obstruction
how do you manage a patient with hirschprungs?
resection of the aganglionic segment/colostomy
what is croup? which patients is it common in?
acute laryngotracheobronchitis - common in patients <6 years
features of croup?
stridor, barking cough, hoarseness, virally unwell
what causes croup?
parainfluenza
how do you manage croup?
- Dexamethasone
2. Nebulised adrenaline (call anaesthatist)
how does epiglottitis present differently to croup?
sudden onset, soft continues snorring stridor, drooling scretions, voice muffled
caused by H.Influenza B
how do you manage epiglottitis?
do not examine throat - call ENT and anaesthetics
IV Abx and steroid
what causes bronchiolotis?
RSV
features of bronchiolitis?
cough, coryza, fever, raised RR, wheeze, inspiratory crackles
signs of bronchiolitis?
reduced feeding, resp distress, hypoxia
how do you manage bronchiolitis?
O2, NG feed
commonest cause of pneumonia? (CAP)
strep.pneumoniae
signs that a patient has pneumonia?
high temperature, malaise, reduced feeding, resp distress, increased RR, reduced SpO2, grunting, intercostal recessions
when do you admit a patient with pneumonia?
respiratory distress signs or SpO2 <92%
how do you manage a viral induced wheeze?
SABA + steroids
signs of a viral induced wheeze over asthma?
virally unwell, no history of atopy/eczema, patient <5 years old
Name a DD of a child presenting with an asthma attack?
foreign body, pertussis, croup, pneumonia
what general measures do we do for asthma patients?
annual review of symptoms/exaccerbations/med use
check inhaler technique and adherence
personalised action plans
what drug therapy do we use for day to day management of asthma?
- SABA (salbutamol)
- Steroid (beclometasone)
- <5 = LTRA (monteleukast), >5 = LABA (salmeterol)
- increasing steroid dose
- prednisolone
how do you manage a child presenting with an acute asthma attack?
- sit patient up, high flow O2
- nebulised salbutamol and ipratropium bromide
- IV hydrocortisone
ESCALATE - MgSO4, aminophylline, IVI salbutamol/ICU
name some pitfalls in asthma management?
bad inhaler technique
reduced perception of severe attacks
satisfied with poor control
don’t notice diurnal variation
how to children present with a UTI?
non-specifically unwell, collapse, sepsis, vomiting, failure to thrive, colic
what is vesicoureteric reflux? why is it relevant?
backflow of urine from the bladder into the ureter
- predisposes children to UTIs
- causes renal scarring
- ureters displaced laterally upon entry to the bladder
how can you investigate UTIs in children? what do they show?
micturating cystourethogram - shows the VUR
DMSA - shows renal scarring
urine dipstick/clean catch sample - microscopy and culture
US kidney and urinary tract
main cause of a UTI?
E.Coli
treatment for a UTI in a child?
GENERAL: avoid constipation, increase fluids, full voiding, repeat MSU
ABX
- < 3 months - amoxicillin and gentamycin
- > 3 months - trimethoprim
- pyelonephritis - gentomycin
name some causes of nephritic syndrome?
post strep
HSP
alport syndrome
SLE
presentation of nephritic syndrome?
haematuria, oliguria, HTN, oedema, loin pain
signs that nephritic syndrome is caused by post strep? how do you manage this?
7-21 days after a sore throat
10 days penicillin
signs that nephritic syndrome is caused by HSP? what is HSP? how do you manage this cause?
IgA vasculitis, purpuric rash on buttocks
steroids and immunosuppressants
signs that nephritic syndrome is caused by Alport syndrome? how do you diagnose this?
x linked recessive inheritance
bilateral SN deafness
genetic testing
what investigations do you do for nephritic syndrome?
FBC, UE, bicarb, Ca, Ph, complement C3 and C4, dsDNA Abs, ANA Abs, ANCA Abs, blood cultures, throat swab, MSU (red cells/white cells, red cast cells, culture)
Renal US/CXR
General management for nephritic syndrome?
sodium restricted diet
diuretic
antihypertensive
what is the triad of nephrotic syndrome?
oedema, proteinuria, hypoalbunaemia
commonest cause of nephrotic syndrome?
minimal changes
signs of nephrotic syndrome in a child?
periorbital/scrotal oedema, anorexia, GI disturbance, frothy urine
how do you manage nephrotic syndrome?
restrict fluid and salt
prednisolone
monitor BP
name some causes of CKD in children?
congenital dysplastic kidneys
ADPKD
reflux nephropathy
what age does nocturnal enuresis normally stop?
age 3/4
how can you manage a child with nocturnal enuresis?
- underlying cause? DM/UTI/constipation
- advise on fluids/toilet advice/intake
- reward systems - star charts, enuresis alarm
- Desmopressin
what are the signs of hypospadias?
abnormal penis - ventral urethral meatus, hooded prepuce, chordee
what is the triad of haemolytic uraemic syndrome?
AKI, microangiopathic anaemia, thrombocytopenia
how does a Wilm’s tumour present?
abdo mass, painless haematuria, flank pain, anorexia
features of a retinoblastoma
loss of red reflex, strabismus, visual problems
how can you manage a retinoblastoma?
external beam radiotherapy, photocoagulation
name 2 common bone tumours in children?
osteosarcoma
ewing’s sarcoma
what are the X ray changes on an osteosarcoma?
Codman’s triangle - periosteal elevation and sunburst pattern
what are the X ray changes on ewing’s sarcoma?
Onion ring lesions
where do neuroblastoma’s arise from?
arise from neural crest tissue of the adrenal medulla and the sympathetic nervous system
what are the features of neuroblastomas?
abdo mass, pallor, weight loss, bone pain, limp
name some complications of undescended testes?
infertility, torsion, cancer
what increases the risk of undescended testes?
pre-term delivery
what are the signs of testicular torsion (twisting of the spermetic cord)?
pain severe, lower abdo pain, N&V
which reflex is lost in testicular torsion?
cremasteric reflex
how do you manage testicular torsion?
urgent surgical exploration
signs that a child is being affected by GORD?
child is WELL
recurrent regurgitation after eating (not projectile)
still thriving
Ix for GORD in children?
24hr pH test in the oesophagus
how do you manage a child with GORD?
ADVISE: normally improves by 1 year of age as the LOS matures
avoid overfeeding/lying down to eat
medication: Omeprazole, gaviscon, ranitidine
when does pyloric stenosis present and why?
presents at 2-8 weeks of age
pyloric muscle hypertrophy which causes a gastric outlet obstruction
what are the electrolyte disturbances in pyloric stenosis?
hypokalaemia
hypochloridaemia
metabolic alkalosis
how can you investigate a child for pyloric stenosis?
feed child –> relax stomach –> visible gastric peristalsis and an olive mass
US the stomach
Mx for pyloric stenosis?
correct UEs, fluids
pyloromyomectomy
name some common causes for gastroenteritis?
rotavirus, norovirus, E.Coli, salmonella
what do you need to assess in a child presenting with gastroenteritis?
DEHYDRATION STATUS
what is meckels diverticulum?
ileal remenant of vitello-intestinal duct
how can meckels diverticulum present?
painless rectal bleeding, volvulus, intesussuption
what is intessusuption?
bowel invaginating on itself proximally
how does intessusuption present?
periods of intense paina nd drawing up the knees
redcurrent jelly stool
shock
sausage mass
management of intessusuption?
1st line = air enema
2nd line = reduction via laparotomy
what is constipation?
hard stool, reduced frequency of defacation
pain
overflow diarrhoea
name some causes of dehydration?
dehydration reduced fibre intake hirschprungs disease hypothyroid anorectal abnormalities
how does constipation lead to incontinence?
- longstanding constipation
- rectum overdistends
- reduced rectal sensation
- involuntary soiling
how can you manage constipation in children?
explain to parents
stool softener e.g. Movicol (escalating regime)
senna - stimulant laxative
what is the commonest hernia in children?
Inguinal - due to patent processus vaginalis - bulge appears when crying
how do you manage a hernia? (2/6 rule)
<6 weeks - operate in 2 days
<6 months - operate in 2 weeks
<6 years - operate in 2 months
what is kawasaki disease and what are the signs?
inflammatory vasculitis
fever > 5 days, cervical lymphadenopathy, cracked lips, peeling fingers, conjunctivitis, coronary artery aneurysms
Ix kawasaki disease?
ESR/CRP, ECHO
Mx for kawasaki disease?
aspirin
IVIG
follow up ECHO
Signs of measles?
cough, coryza, conjunctivitis, cranky, high temperature, maculopapular rash behind ears which spreads down body, koplik spots
Ix for measles?
IgG/IgM, PCR
name some complications of measles?
croup
pneumonia
subacute sclerosing paraencephalitis
what are the signs of rubella? when is it infectious?
mild illness
macular rash starting on face
infectious 5 days before rash to 5 days after rash started
effects of rubella on a foetus?
deafness
cataracts
CHD
how do the skin lesions develop in chicken pox?
2 day temp –> macular –> papular –> pustules –> crust
lesions tend to occur on the trunk
complications of chicken pox?
pneumonia
secondary infection
meningitis
how can you manage the symptoms of chicken pox?
calamine lotion
trim nails
name some meningial signs?
stiff neck, positive kernig and bruduski, photophobia
name some septic signs?
raised heart rate and resp rate, reduced BP, mottled and cold peripheries
name a sign of meningococcal disease?
non-blanching purpuric/petichial rash
how do you manage meningococcal disease?
- IMMEDIATE BENPEN before hospital (IM)
2. Hospital - ABCDE, IV cefotaxime + dexamethasone
how do you Ix acute bacterial meningitis?
throat swab PCR
blood/urine/stool culture
head CT
LP
what are the signs of encephalitis?
flu-like illness, low GCS, raised temperature
what is the main cause of viral encephalitis?
HSV
what are the 3 main features of ADHD?
- impulsivity
- inattention
- hyperactive
how do you investigate ADHD?
school reports, conners scale, observe in school, screen for an organic cause
how do you manage ADHD?
parenting lessons, positive parenting
education programmes
methylphenidate
name the 3 features of autism?
- impaired social interaction - unaware of others/no empathy/solitary play
- impaired imagination - less babbling/no facial expressions/no fantasy play
- poor range of activities - object pre-occupation
how can you manage autism?
intensive early speech and social therapy
national autism society
social training
risperidone
what is cerebral palsy?
disorder of movement/posture caused by a non-progressive lesion to the brain occuring < 2 years
name some features of cerebral palsy?
epilepsy
delayed motor milestones
learning disability
language/speech problems
how can you manage a patient with cerebral palsy?
physio/OT/ortho surgeons
botox
baclofen injections
what is klinefelter syndrome? signs?
47XXY
infertility, hypogonadism, gynocomastia
what is pattau syndrome? signs?
trisomy 13
cardiac and renal impairment, cerebral malformation, polydactyl, neural tube defect, cleft palate, micropthalmia, SGA
what is edwards syndrome? signs?
trisomy 18
rockerbottom feet, SGA, overlapping fingers, renal and cardiac malformation, cerebral malformation, low set ears, prominant occiput
what is turners syndrome? signs?
45X
wide and spade shaped chest, wide nipples, coarction of aorta, horseshoe kidney, recurrent OM, primary amenorrhea, short stature
what is prader willi? signs?
loss of paternal genes on chromosoem 15. hypotonia, poor feeding - obesity and social problems
what is angelman syndrome? signs?
loss of maternal genes on chromosome 15. laughing fits, physical and intellectual disability
what is a sign of noonan’s syndrome?
ptosis and down turned eyes
what is downs syndrome and what are the signs?
trisomy 21
flat occiput, low set ears, small eyes and mouth, large tongue, round face, short stature, epicanthal fold, single palmar crease
what diseases are associated with downs syndrome?
coeliac disease, hirschprung, duodenal atresia, AD, leukaemia
what is the 3 ways that downs syndrome is inherited?
non-meiotic dysfunction
robertsman translocation
mosaicism
what is the defintion of precocious puberty?
<8 in girls, and <9 in boys
name some gonadotropin dependant causes of precocious puberty (raised LH/FSH)
pituitary tumours
name some gonadotropin independant causes of precocious puberty (low FSH/LH)
tumours in the gonads
what do we use to stage puberty?
tanner’s chart
Ix for precocious puberty?
stage the puberty CT/MRI head bone age (skeletal Xray) T4/TSH/LH/FSH/HCG/AFP/GH US ovaries and adrenals
what are some risk factors for nectrotizing enterocolitis?
premature, cows milk
what are the signs of nectrotizing enterocolitis?
rectal bleeding, abdo distension, mucus PR, tender, shock
what is the classic XRay sign of nectrotizing enterocolitis?
pneumonitis intestinalis (gas in the bowel wall)
how do you manage nectrotizing enterocolitis?
stop feed, culture faeces, cross match blood
Abx (cefotaxime + vancomycin)
what increases the risk of meconium aspiration?
increasing gestational age
distressed foetus
what does aspiration of meconium cause?
chemical pneumonitis
obstruction
surfactant dysfunction
how do you manage meconium aspiration?
ventilation
ABx
NO
surfactant
what causes respiratory distress syndrome?
surfactant deficiency (RF = prematurity)
which cells secrete surfactant?
type 2 pneumocytes
How can you prevent RDS?
antenatal corticosteroids - stimulates surfactant production
Features of RDS? on XRay?
raised RR, chest wall recessions, grunting, nasal flaring
ground glass appearance
what is the DD of RDS?
meconium aspiration, transient tachypnoea of the new born
how do you manage RDS?
Ventilate (21% O2)
ET surfactant therapy
what is a side effect of ventilation for RDS?
bronchopulmonary dysplasia - caused by barotrauma and O2 toxicity
what are the features of bronchopulmonary dysplasia?
O2 desaturations during feeding
leads to;
- low IQ
- cerebral palsy
- asthma
- exercise intolerance
what are the signs of toxoplasmosis infection?
retinopathy, cerebral calcifications, hydrocephalus
what are the signs of a parovirus B19 infection?
fetal hydrops
what are the signs of a rubella infection?
deafness, CHD, cataracts
what are the signs of a CMV infection?
SN deafness, liver dysfunction, SGA
signs of a listeria infection?
sepsis
name some causes of hypoxic ischaemic encepalopathy?
cord prolapse
placenta abruption
maternal hypoxia
inadequate post natal circulation
how do you manage HIE?
treat seizures
therapeutic hypothermia
what are the physiological reasons for jaundice in a newborn?
increased production (short RBC lifespan)
hepatic immaturity
breast feeding can cause dehydration and reduced bilirubin elimination
causes of jaundice in a baby <24 hours old?
RhD, ABO incompatibility, sepsis, G6PD/spherocytosis
how do you investigate jaundice within 24 hours of birth?
COOMBS test, FBC plus film
what does coombs test show?
presence of antibodies on a babies RBCs
what is a cause of jaundice in a baby > 2 weeks?
sepsis, TORCH infection, breast milk, biliary atresia
how do you investigate jaundice >2 weeks?
TORCH screen, sepsis 6, US liver
what is biliary atresia?
congenital malformation of the bile duct causing accumulation of bile
what is Kernicteris?
acute bilirubin encepalopathy
signs of Kernicteris?
shrill cry, lethargy, poor feeding
how do you manage Kernicteris?
phototherapy, exchange transfusion
what are the long term effect of Kernicteris?
akethoid dyskinetic cerebral palsy
what is the presentation of transient synovitis?
follows a viral infection - limp and pain, comfortable at rest, no temperature or toxic signs
what Ix do you do for transient synovitis? what do these show?
US hip - effusion
what is the criteria for septic arthritis?
KOCHER CRITERIA
- not weight bearing
- temperature
- raised ESR/CRP/WCC
common cause of septic arthritis?
S.Aureus
how do you IX septic arthritis?
FBC, UE, LFT, blood cultures, ESR, CRP, aspirate joint
what is osteomyelitis and what bacteria commonly causes it?
Infections of the metaphysis of bone (normally the long bones in children)
S.Aureus
how do you investigate osteomyelitis?
WCC/ESR/CRP/bone biopsy - gold standard
what are the XRay changes shown early and late in osteomyelitis?
EARLY - cloccae (erosions in the bone) LATE - - involcurum (elevated periosteum) - sequestrum (dead bone) - sinuses (discharging pus)
Mx for osteomyelitis?
6 weeks of Cefotaxime and Vancomycin
what is DDH?
stable acetabular dysplasia through to total dislocation
what increases the risk of DDH?
breech, oligohydramnios, twin, sibling with DDH
when and how do we screen childrens hips?
at 1 day and at 6 weeks
ORTOLANI - flex hips and abduct to try and lift femoral head to relocate hips
BARLOW - flexed hips and adduct the apply axial load
what do you do of ortolani and barlow comes back as abnormal?
US hips
how do you manage DDH?
Pavlik harness, surgery
definition of JIA?
> 6 weeks of joint swelling and stiffness in a child <16
what types of JIA are there?
polyarthritis = >4 joints oligoarthritis = <4 joints systemic = fever and salmon rash
features of JIA?
morning stiffness, joint swelling, can’t participate in hobbies, reduced growth, joint deformity
name some complications of JIA?
uveitis, reduced growth, osteoporosis, anaemia
how do you manage JIA?
involve paeds rheumatology NSAIDS/paracetamol corticosteroids - in the joint or systemic MTX infliximab
what is rickets?
failed mineralisation of growing bone
what increases your risk of rickets?
dark skin, low UV exposure, malabsorption, vegan diet, CF, coeliac disease, maternal vitamin D deficiency
name some signs of rickets
harrison's sulcus palpable costo-chondral joint ping pong sensation on the head widened wrists delayed fontanelle closure
how do you investigate rickets?
Vit D and calcium levels
X ray wrist
what is congenital adrenal hyperplasia (CAH)?
autosomal recessive disorder. Deficiency of the 21a hydroxylase enzyme. Reduced gut cortisol results in negative feedback and increased ACTH and increased testosterone levels
Reduced mineralcorticoid synthesis (low Na and high K)
features of a patient with CAH?
clitoris hypertrophy fused labia enlarged penis salt losing crisis tall
what do you find on Ix with a patient with CAH?
low Na, high K, low glucose, metabolic acidosis
high testosterone
US female - ovaries?
how do you manage a patient with CAH?
genital surgery for females
fludrocortisone/hydrocortisone
monitor growth
Name the features of a L –> R shunt (breathless)?
PDA
ASD
VSD
How do you investigate cardiology in children?
antenatal ECHO, ECHO/ECG/CXR
Features of PDA? Mx?
ductus arteriosus remains open - continuous murmer.
need to shut with a coil
features of ASD? what murmur do you hear?
recurrent chest infections and wheeze
Left upper sternal edge ejection systolic murmer
features of VSD?
left lower sternal edge pansystolic murmer
Name the causes of a R –> L shunt (cyanotic)?
Tetralogy of Fallot
transposition of the arteries
what are the features of ToF?
overriding aorta
VSD
pulmonary stenosis
RVH
what symptoms do you get with ToF?
what sort of murmer do you get?
symptoms of cyanosis and hypercyanosis on defacation/exercise
Harsh ejection systolic murmer
what is the transposition of arteries and what symptoms do you get?
arteries are switched over - severe cyanosis at day 2 as the ductus arteriosus closes. NO MURMER
how do you manage transposition of the arteries?
give prostaglandin and a atrial septoplasty - to allow for mixing of blood
surgical repair
name the causes of an outflow obstruction in a well child?
pulmonary stenosis
aortic stenosis
name the causes of an outflow obstruction in an unwell child?
coarction of the aorta
what murmer is there in pulmonary stenosis?
soft ejection systolic murmer in the Left upper sternal edge
what murmer is there in aortic stenosis?
ejection systolic murmer in the right upper sternal edge
what are the features of coarction of the aorta?
restriction around ductus arteriosus
Radiofemoral delay
ejection systolic murmer
LV hypertrophy
what causes Kwashiokor?
reduced protein intake
what causes Marasmus?
lack of calories
signs of diptheria?
muffled voice, dysphagia, bronchopneumonia, airway obstruction, tonisillitis with false membrane over the fauces
how do you manage a patient with diptheria?
diptheria antitoxin and erythromycin
features of Kallman syndrome?
X linked recessive disorder LACK OF SMELL delayed puberty hypogonadotropic hypogonadism low sex hormones (FSH and LH)
what is osteogenesis imperfecta?
brittle bone disease due to a disorder of collagen metabolism which results in fragility and fractures
features of osteogenesis imperfecta?
childhood presentation
fractures after minor trauma
blue sclera
deafness secondary to osteosclerosis
how do you investigate osteogenesis imperfecta?
Ca/Ph/PTH/ALP all NORMAL
What is perthes disease?
avascular necrosis of the femoral head. Impaired blood supply and bone infarction.
features of perthes disease?
10% bilateral
hip pain over a few weeks and a limp
stiffnes
reduced RoM
Xray changes in perthes disease?
early - widened joint space
late - reduced femoral head size
how do you investigate perthes disease?
Xray/bone scan - CATTERALL STAGING
how do you manage perthes disease?
cast/brace, surgery
which bone does Kohler disease affect?
Navicular bone
presentation of Kohler disease and features on X ray?
pain in mid-tarsal region and a limp
X Ray - dense and deformed bone
what is Osgood Schlatter disease?
inflammation of the tibial tuberosity in association with physical overuse - the pain occurs on strenuous activity and contraction of the quadricep
what does an X ray show in osgood schlatter disease?
tibial tuberosity enlarged
how do you manage osgood schlatter disease?
ice, oral anti-inflammatories, physio
what is a slipped femoral epiphysis?
displacement through the growth plate - the epiphysis slips down
presentation of a slipped femoral epiphysis?
50% patients obese
follows minor trauma - limp and groin pain
LIMITED flexion/abduction/medial rotation
how do you investigate a slipped femoral epiphysis?
AP X ray of the hip
frog leg X ray
how do you approach newborn resuscitation?
- Dry baby and keep warm
- Assess tone/RR/HR
- if gasping/not breathing –> 5 inflation breaths
- reassess chest movements
- If HR < 60bpm –> start compressions and ventilation breaths at a ratio of 3:1
features of a febrile convulsion?
viral infection and raised temperature
seizure lasting <5 mins
tonic-clonic
Mx of a febrile convulsion?
rectal diazepam, antipyretic
what are the 4 areas of development that we assess?
social
gross motor
fine motor and vision
speech and hearing