Paediatric Neonatology Flashcards
Main Issue in neonatal Resuscitation
hypoxia
baby has large sa: weight ratio= get cold very easy
baby born wet, lose heat rapid
baby born through meconium = in mouth/airway
explain hypoxia in neonates at birth
issues etc
normal labour and birth leads to hypoxia
when contractions happen placenta cant carry out normal gas exchange= hypoxia.
extended hypoxia , leads to anaerobic rep = drop in fetal hr = bradycardia
further hypoxia= reduced gcs = drop in resp effort. if to the brain = hypoxic-ischaemic encephalopathy = can lead to cerebral palsy
principles of neonatal resuscitation
- dry baby and maintain temp
- assess tone , resp rate, hr
- if gasing or not breathing give 5 inflation breaths. ( 2 cycles of 5 breaths 3 seconds each to stimulate breathing and hr) if not 30secs ventilation breaths. if no then chest compressions.
- reassess -chest movements
- if hr not improving and less than 60bpm start compressions and ventilation breaths at a rate of 3:1.
iv drugs and intubation - if risk of hypoxic-ischaemic encephalopathy
(inflation breaths different from ventilation breaths. its for keeping pressure to open lungs)
ways to get baby warm
how does this help
neonatal resus
vigorous drying stimulates breathing
warm delivery rooms
heat lamp
if under 28 weeks place in plastic bag while still wet - manage under heat lamp
what is the APGAR score and when is it calculated
score total out of?
findings?
neonatal resus
1,5,10 mins whilst resus continues.
indicator for progress
/10
each topic 0,1,2
appearance - blue/pale centrall, blue extremeties, pink
pulse - absent, under 100, over 100
grimace - no response, little, good
activity - floppy, flexed arms/legs, active
respiration - absent, slow/irregular, strong/crying
when performing inflation breaths, what should be used in term, pre term babies
aim of ox sat
air - near term
air and oxygen - pre-term babies.
aim for gradual rise, not exceed 95%
what is delayed umbilical cord clamping
benefits
drawbacks
how much should you delay in uncompromised neonate.
a lot of fetal blood vol in placenta after birth. if delayed it can enter baby circulation. - placental transfusion
improved haemoglobin, iron, bp and reduced intraventricular haemorrhage and necrotising enterocolitis.
neonatal jaundice- need more photo therapy
at least 1 minute
What is respiratory distress syndrome?
caused by?
affects who
when?
cxr sign
premature neonates
born before lungs start producing enough surfactant.
below 32 weeks
ground glass appearance
pathophysiology of respiratory distress syndrome
inadequate surfactant = high surface tension within alveoli.
leads to atelactasis - lung collapse because its harder for alveoli and lungs to expand. =
inadequate gas exchange = hypoxia, hypercapnia, resp distress
how would you manage respiratory distress syndrome?
mother
premature neonate
antenatal steroids - dexamethasone - give to mother with suspected/confirm preterm labour so you get more surfactant production.
reduces incidence of severe resp distress syndrome.
premature neonate:
- intubation and ventilation - assist breathing
- endotracheal surfactant - artificial delivered into lungs via endotracheal tube.
- continuous positive airway pressure (cpap) - via nasal mask helps keep lungs inflated whilst breathing
- supplementary ox - 91-91% in preterm neonates
comps of resp distress syndrome
short term
long term
pneumothorax
infection
anpoea
intraventricular haemorrhage
pulmonary haemorrhage
necrotising entercolitis
chronic lung disease of prematurity
retinopathy of prematurity - more often more severly in neonates with rds
neurological hearing and visual impairment
What is bronchopulmonary dysplasia?
affects who
what other condition do they have
diagnosis made how?
tx?
chronic lung disease of prematurity.
premature babies - before 28 weeks gestation
these babies have respiratory distress syndrome and need oxygen therapy or intubation and ventilation at birth.
diagnosis : cxr changes
they require ox therapy after they reach 36 weeks gestation
features of bronchopulmonary dysplasia?
low ox sats
increased work of breathing
poor feeding and weight gain
crackles and wheezes on chest auscultation
increased susceptibility to infection
how to prevent bronchopulmonary dysplasia?
give corticosteroids – betamethasone to mothers that show sign of premature labour at less than 36 weeks gestation.
neonate born:
- using CPAP rather than intubation and ventilation
- use caffeine to stimulate resp effort
- not over oxygenating with supplementary oxgyen
how would you manage bronchopulmonary dysplasia?
what do you have to protect against?
how to treat?
do formal sleep study and assess ox saturations during sleep.
can discharge baby on low dose ox at home - 0.01 litres per min via nasal canula. follow up to wean ox level over 1st yr of life
protect against respiratory syncytial virus -RSV : reduce risk of severity of bronchiolitis.
monthly injections of monoclonal antibody against virus - palivizumab.
risk factors of respiratory distress syndrome
male
diabetic mother
c section
second born of premature twins
clinical features of resp distress syndrome pt
tachynpnoea
intercostal recession
expiratory grunting
cyanosis
what is meconium aspiration syndrome?
more common in?
can cause?
higher rates if hx of ?
resp distress in newborn due to meconium in trachea.
occurs in immediate neonatal period.
more common in post term deliveries.
can cause severe respiratory distress.
maternal htn , pre-eclampsia, chorioamnionitis, smoking or substance abuse
