pack 3 Flashcards
What is the different types of vitamin A?
They are Retinoids:
Retinol: A primary alcohol
Retinal: An aldehyde derived from the oxidation of retinol
Retinoic acid: Carboxilic acid derived from the oxidation of Retinal.
b-Carotene: Plant form
Vitamin A is used to treat what?
Psoriasis
Leukemia
Severe acne
What does Vitamin A def cause?
Night blindness
xerophthalmia, a pathologic dryness of the conjunctiva and cornea
What form of vitamin A is used to treat acne?
Isotretnoin (Roaccutane)
13-cis-retinoic acid
Causes dryness of skin
What is the inactive and active form of Vitamin D3 called? How is it activated?
Inactive: 7-dehydrochlestrol
It is activated by:
In the liver: 25- hydroxylation (calcidiol)
In the kidney: 1-hydroxylation (Calcitriol)
Active form: 1,25-Dihydroxycholecalciferol
What is the conversion of 7-dehydrocholestrol to 1,25-dihydroxycholecalciferol regulated by in the kidney?
Parathyroid hormone
What are the two types of vitamin D def?
Rickets: in children
Osteomalacia: In adults
What is another name for vitamin E?
Tocopherol
What are the types of vitamin E/tocepherol? Which one is used in humans?
Types: From Alpha till theta tocepherol
Used in humans: a-tocepherol
What is the function of vitamin E?
Vitamin E is an antioxidant
Stops the chain reaction of free radicals
Protects the oxidation of LDLs
What is are the forms of Vitamin K?
phylloquinone, menaquinone, and menadione
What is the function of Vitamin K?
Blood Klotting