P3: Pancreatic Enzymes

Question 1

hormones (produced directly to
the bloodstream)

Answer 1

endocrine

Question 2

enzymes (exit in the pancreatic
duct)

Answer 2

exocrine

Question 3

Activators of amylase: ___________ and ___________

Answer 3

Calcium and Chloride

Question 4

● Breakdown of starch and glycogen to
monosaccharides

Answer 4

amylase

Question 5

2 amylase tissue sources

Answer 5

● Salivary glands
● Acinar cells of the pancreas

Question 6

Salivary AMS also known as _______

Answer 6

ptyalin

Question 7

○ Pancreatic AMS

Answer 7

● Acinar cells of the pancreas

Question 8

molecular weight of amylase

Answer 8

● MW: 50,000 - 55,000

Question 9

● Readily filtered by the glomerulus

Answer 9

amylase

Question 10

Initial digestion of starch by salivary
amylase

Answer 10

mouth

Question 11

○ Final digestion by pancreatic amylase

Answer 11

● Small intestine

Question 12

● P-type isoamylase have __________

Answer 12

pancreas

Question 13

● S-type isoamylase have ________, ________, _________

Answer 13

○ Salivary gland
○ Lungs
○ Fallopian tubes

Question 14

p3 is predominant in ________________

Answer 14

acute pancreatitis

Question 15

AMYLASE

○ Rise:________ after the onset of an attack
○ Peak: __________
○ Normalize: _________

Answer 15

○ Rise: 5-8 hours after the onset of an attack
○ Peak: 24 hours
○ Normalize: 3-5 days

Question 16

sudden inflammation of the
pancreas

Answer 16

acute pancreatitis

Question 17

Inflammation of parotid gland

Answer 17

Parotitis

Question 18

Acute pancreatitis

The first and the most common risk
factor is the _________

Answer 18

ALCOHOL

Question 19

Secretion of protein-rich pancreatic fluid that
leads to the deposition of thickened protein
plugs and obstruction of small pancreatic
ducts

Answer 19

● Alcohol and Pancreatitis

Question 20

Amylase is high in normal condition

Answer 20

Hyperamylasemia

Question 21

Persistent increase in serum amylase is
seen without clinical symptoms

Answer 21

Macroamylasemia

Question 22

○ AMS molecule combines with IgG or IgA

Answer 22

Macroamylasemia

Question 23

Hydrolyzes the ester linkages of fats to produce
alcohols and fatty acids

Answer 23

lipase

Question 24

__________ break down Triglycerides/Large fat
molecules into simpler form; alcohol and
fatty acids

Answer 24

Lipase

Question 25

○ __________ binds in the ester linkages of fats: 1,3
ester linkage

Answer 25

Lipase

Question 26

LIPASE

● Primarily in __________

Answer 26

Pancreas

Question 27

● Also present in_________, ________, _______, ________, __________, _______

Answer 27

liver, stomach, small intestine, white
blood cells, fat cells and milk (Henry)

Question 28

Almost exclusive to the diagnosis of acute
pancreatitis

Answer 28

lipase

Question 29

LIPASE

○ Rise: ________ after onset of an attack
○ Peak: ___________
○ Persists for about: _________
__________ rise suggests poor
prognosis or pancreatic cyst

Answer 29

4-8 hours
24 hours
8-14 days

> 14 days

Question 30

molecular weight of lipase

● MW: ___________

Answer 30

45,000

Question 31

○ Reverse this inhibition

Answer 31

Colipases

Question 32

Smaller than the amylase

Answer 32

Lipase

Question 33

NOT present in the _________ because it was
reabsorbed in the tubules

Answer 33

urine