Oxygenation Flashcards
What is Angina?
A clinical manifestation of reversible myocardial ischemia
What causes Chronic Stable Angina?
Coronary Artery Disease
What is the term for when heart muscle demands more oxygen than it is supplied?
Ischemia
In ischemic conditions, how long will cardiac cells last?
20 minutes
At what percentage do blocked arteries generally begin causing pain?
75% blockage
How long must a coronary occlusion last before the myocardium becomes hypoxic?
10 seconds
If an occlusion lasts longer than 10 seconds, what happens?
Anaerobic metabolism begins, which build lactic acid
Why does anaerobic metabolism cause pain?
Lactic acid irritates the myocardial nerve
Why does the pain “radiate” to the shoulders or arms?
Because the myocardial nerve trasmits a pain message to the cardiac nerves and the upper thoracic nerves
What does the PQRST chest pain assessment stand for?
P = precipitating events Q = quality of pain R = radiation of pain S = severity of pain T = timing
Pain from chronic stable angina is usually NOT characterized how?
Sharp or stabbing
What would an EKG show in the event of an event of angina?
ST depression or T wave inversion
Patients with what disease are most like to have silent ischemia?
Diabetes
What is chest pain at night called?
Nocturnal angina
What is chest pain when lying down called?
Decubitus angina
What is Prinzmetal’s Angina?
Angina at rest due to coronary artery spasm
What is the primary treatment of Prinzmetal’s angina?
Calcium channel blockers
What is microvascular angina?
Angina from myocardial ischemia due to abnormalities or blockages of the coronary microcirculation
Who does microvascular angina primarily affect?
Women
What is the “first line of therapy” for treatment of angina?
Short-acting nitrates
What should a patient on short acting nitrates be told?
- it causes a headache
- protect the bottle from light
- replace bottle every 6 months
What is ABC major treatment of Chronic Stable Angina?
A = Anticoagulant, Antianginal, ACE inhibitors and angiotensin receptor blockers. B = Beta-blockers and blood pressure meds. C = Cigarette-cessation, Calcium channel blockers and cholesterol management. D = Diet and diabetes control. E = Education and exercise F = Flu vaccine
What class of drugs all end with “lol”?
Beta-blockers
People with what pre-existing condition should not take Beta-blockers?
Asthma