Oxidative Phosporylation Flashcards

1
Q

Oxidative phosphorylation occurs in the

A

Inn,er membrane of the mitochondria

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2
Q

Endergonic (non spontaneous) reactions happen in the body by

A

High levels of reactants

Products are constantly used up in other reactions (example OAA)

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3
Q

Coupled reactions occur when the energy requiring reactions and the energy yielding reactions share a

A

Common intermediate

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4
Q

Contraction of muscles is fueled by

A

ATP

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5
Q

In complex 1 of the ETC electrons are transferred from________and outputs______H atoms

A

NADH to coenzyme Q (Ubiquinone); 4

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6
Q

In complex 3 of the ETC, electrons are transferred from________which outputs____H atoms

A

Coenzyme Q to cytochrome c; 4

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7
Q

In complex 4 of the ETC electrons are passed from________, reducing it to water and outputting_____H atoms

A

Cytochrome c to O2; 2

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8
Q

In complex 2 of the ETC, electrons are transferred from_______with no output of hydrogen

A

FADH2 to coenzyme Q

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9
Q

Complex 2 contains the enzyme

A

Succinate dehydrogenase

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10
Q

Coenzyme Q is lipid soluble. T/F

A

True

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11
Q

__________inhibits complex 1 and causes NADH to accumulate

A

Rotenone

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12
Q

________blocks the passage of the electrons through complex 3

A

Antimycins

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13
Q

__________and _______combine with complex 4 (cytochrome oxidase) and block the transfer of electrons to O2

A

Cyanide and carbon monoxide

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14
Q

What is the function of uncoupling proteins

A

They dissipate the proton gradient by transporting protons back into the mitochondria without the ATP synthase

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15
Q

A classic uncoupling protein in the ETC is

A

DNP

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16
Q

UCP1 is a coupling protein found in the mitochondria of______and heat is generated in this process

A

Brown adiposytes tissue