overview of metabolic pathways Flashcards

1
Q

_______ accounts for roughly 75% of total energy expenditure in sedentary people

A

Resting Metabolic Rate (RMR)

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2
Q

The primary determinant of RMR is ________

A

fat free mass (lean body mass).

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3
Q

In normal individuals this accounts for roughly 8% of total energy expenditure

A

Thermic Effect of Food (TEF)

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4
Q

Rank the Macro nutrients from the highest TEF to the lowest .

A

1) protein
2) Carbohydrates
3) Fat

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5
Q

what is non-exercise activity thermogenesis (NEAT).

A

This is energy expended in movement that is “unconscious” or unplanned. Some people call this “fidgeting” or movements that we all do while we are engaged in other tasks.

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6
Q

The ratio of work to total energy expended during physical activity is known as _______

A

exercise/work efficiency

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7
Q

Total energy expenditure can be measured most accurately using a method called _______ which measures oxygen consumption in free living individuals over a period of weeks

A

“doubly labeled water”

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8
Q

Most people under-report food intake by ________.

A

20% to 40%

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9
Q

A loss of _________ is associated with severe malnutrition at a point where death often results.

A

30% of body protein

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10
Q

what are the methods to measure body fat

A

1) body mass index (weight in kg/height2 in meters), 2)skin fold thickness,
3) bioelectrical impedance,
4) body density measurements (by underwater weighing or air displacement)
5) dual energy x-ray absorptiometry (DEXA).

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11
Q

________ is the most accurate way to measure body composition.

A

dual energy x-ray absorptiometry (DEXA)

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12
Q

what is an anabolic process.

A

A process of synthesizing more complex molecules from simpler ones

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13
Q

what does the Pentose Phosphate Pathway (Hexose Monophosphate Shunt) generate?

A

NADPH and ribose (5 carbon) sugars

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14
Q

NADPH (not to be confused with NADH) provides energy for the synthesis of ____ and ______ . It is also important in defending cells against oxidative stress and in pathogen killing by white blood cells

A

fatty acids,

steroid hormones

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15
Q

The ribose sugar Ribose-5-phosphate produced by the Pentose Phosphate Pathway is a key substrate for _________

A

nucleotide synthesis (the building blocks of RNA and DNA)

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