Over view

Question 1

symptoms first appear after

Answer 1

age 60

Question 2

is the most common cause of ____ in people over 65

Answer 2

dementia

Question 3

for every 5 year age group beyond 65 the % of people with AD…

Answer 3

doubles

Question 4

affects more ____ than ____

Answer 4

women than men

Question 5

People with AD are cared for in

Answer 5

assisted living, long term care and/or at home

Question 6

The human brain weighs about…and has about…neurons, and about…synapses

Answer 6

3lbs, 100 billion, 100 trillion

Question 7

The largest and most complex region of the brain…

Answer 7

forebrain

Question 8

plays a major role in emotions and motivation, pain and pleasure

Answer 8

hypothalamus

Question 9

through which all sensory information must pass (except smell) to get to the ——cortex. Also called the…

Answer 9

Thalamus- structure….cerebral cortex,- also called the ‘main relay station’

Question 10

Parts of the limbic system

Answer 10

hypothalamus, amygdala

Question 11

part of the brain associated with memory formation…

Answer 11

Hippocampus

Question 12

Amygdala is involved with

Answer 12

fear and aggression

Question 13

_______ lobe controls sequencing of motor movements, __________ ________, personality and the ability to ….

Answer 13

FRONTAL lobe controls sequencing of motor movements, LANGUAGE PRODUCTION, personality and the ability to PLAN, REASON AND SOLVE PROBLEMS

Question 14

Parietal Lobe integrates……, processes______ information, and allows us to maintain and direct our attention.

Answer 14

Parietal Lobe integrates VISUAL & AUDITORY INFORMATION, processes SPATIAL information, and allows us to maintain and direct our attention.

Question 15

…lobe regulates language comprehension and allows us to…

Answer 15

TEMPORAL lobe regulates language comprehension and allows us to CREATE NEW MEMORIES

Question 16

…integrates visual information

Answer 16

occipital lobe

Question 17

…help measure activity in different parts of the brain during different mental activities

Answer 17

PET: positron emission tomography

Question 18

To stay healthy neurons must…AD_____all three of these things

Answer 18

communicate with one another, carry out metabolism and repair themselves. AD disrupts all three of these things.

Question 19

The brains of people with AD have an abundance of ___ things…

Answer 19

The brains of people with AD have an abundance of 2 things: beta-amyloid plaques and neurofibrillary tangles

Question 20

What is the precursor to Beta-amyloid plaques?

What is the process of creation?

Answer 20

APP: Amyloid precursor protein.

1. app sticks through membrane
2. enzymes cut thee APP into fragments of protein, including beta-amyloid
3. beta-amyloid fragments come together in clumps to form plaques

Question 21

Process of Plaque creation:

1. app sticks through _________
2. _________ cut the APP into fragments of __________, including beta-amyloid
3. __________ come together in clumps to form plaques

Answer 21

1. app sticks through membrane
2. enzymes cut thee APP into fragments of protein, including beta-amyloid
3. beta-amyloid fragments come together in clumps to form plaques

Question 22

________ ________ from clumps which disrupt the process of the __________. This affects the _______ (responsible for forming new memories) and other areas of the cerebral cortex.

Answer 22

Beta-amyloid Plaques from clumps which disrupt the process of the neurons. This affects the hippocampus and other areas of the cerebral cortex.

Question 23

A protein called tau helps…In AD this changes causing…

Answer 23

stabilize microtubules. In AD tau changes, causing microtubules to collapse, and tau proteins clump together to form neurofibrillary tangles.

Question 24

Gene identified as possibly involved in formation of beta amyloid plaques

Answer 24

ApoE: apolipoprotien