Drug interventions Flashcards
Whose responsibility is it to make sure drugs are safe
Health Canada
HC requires drug manufacturers to follow strict procedures in testing drugs they wish to market. The over all process takes about _____ and involves several steps which include:
- ____ &_____research
- __________development
- __________ __________. _____1,2 & 3
- _____________________ Submission.
- Chemical & Biological research
- Pre-clinical development
- Clinical Trial. Phases 1,2 & 3
- New Drug Submission.
Currently there are____ approved for use in the treatment of AD in Canada.
4
Drugs used to treat mild to moderate AD symptoms include:
These are ______ __________ and all have _________ ___________.
Mild-Moderate: Aricept, Reminyl, Exelon
These are CHOLINESTERASE INHIBITORS and all have SIMILAR EFFECTS_.
Another name for Reminyl
galantamine
Another name for Exelon
rivastigmine
Another name for Aricept
donepizil
Another name for Ebixa
memantine hydrochloride
These drugs can help improve some ______ _______ to carry out activities for up to ______ or so.
These drugs can help improve some patient’s abilities to carry out activities for up to a year or so.
Drugs for moderate to severe AD include:
Moderate-Severe: Ebixa
The effects of drugs to improve mild to moderate symptoms of AD include (6)…
improved: attention, memory, alertness, motivation, mood and ability to carry out ADL
ADL stands for…
activities of daily living
Reminyl, ______ & Aricept work by reducing the destruction of_____________ and thereby ____________ it’s activity
Reminyl, EXELON & Aricept work by reducing the destruction of ACETYLCHOLINE and thereby INCREASING it’s activity
___________ ___________ prevent the enzyme from breaking down acetylcholine.
CHOLINESTERASE INHIBITORS
Side effects of ______,_______and Exelon include: (5)
REMINYL, EXELON, ARICEPT Nausea, loss of appetite, tiredness, diarrhea, muscle cramps, sleep disturbance