Ovarian Flashcards
What type of cancer is it usually?
Epithelial carcinoma
What are the risk factors?
Genetics - BRCA HNPCC(colorectal)
Anything that increases oestrogen
- HRT oestrogen only
- Obesity
- 0 parity
- Late menopause
What decreases the risk?
Many children
first child under 25
What are the symptoms?
These are non specific which leads to late diagnosis:
Pelvic pain
Feeling full
Urinary urgency (pressing on bladder)
fatigue, weight loss
what are some signs?
Shifting dullness
Mass
Ascites
How is it diagnosed?
Surgically
How can it be tracked?
CA125
How does it spread and where to?
Intraperitoneal dissemination - often to the peritoneum causing omental cake.
Deposits can appear on any organs and it can block the bowel
Why do ascites occur?
Tumour breaks down barrier between peritoneam and ECF
It blocks lymph
Increase in oncotic pressure in peritoneum due to leak of ECF
What age group is it common in?
Post menopausal