Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

19 Sedative, hypnotic, anxiolytic drugs > Other sedative-hypnotic drugs > Flashcards

Other sedative-hypnotic drugs Flashcards

1
Q

Other sedative-hypnotic drugs - 5 drugs

A 
Zolpidem
Zaleplon
Eszopiclone
Melatonin
Ramelteon
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Zolpidem - MOA

A

Selective targeting of GABAA receptors that are composed of α1 subunits (omega1 site)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Zolpidem - indications

A

Insomnia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Zolpidem and zaleplon - adverse effects

A

Dizziness, drowsiness, headache

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Zolpidem, zaleplon and eszopiclone - interactions

A

Alcohol & CNS depressants: potentiated effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Zolpidem, zaleplon, eszopiclone, ramelteon - duration of action

A

Zolpidem - Short.
Zaleplon - Very short.
Eszopiclone - Short.
Ramelteon - Short.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which of the other sedative-hypnotic drugs are category B for pregnancy?

A

Zolpidem and zaleplon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Zaleplon - indications

A

Insomnia, medsleep awakenings

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Eszopiclone - adverse effects

A

Dizziness, drowsiness, difficulty with coordination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Eszopiclone - indications

A

Insomnia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Melatonin - MOA

A

Principal mediator of the biologic clock that determines circadian, seasonal and reproductive rhythms. Released before onset of sleep and cause drowsiness that facilitates sleep.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Melatonin - indications

A

Jet lags, insomnia in shift-change workers.
Insomnia in elderly pts with melatonin deficiency, delayed sleep-phase syndrome.
Non-24-hour sleep-wake disorder.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Ramelteon - MOA

A

Acts selectively on melatonin receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Ramelteon - indications

A

Sleep-onset insomnia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Ramelteon - contraindications

A

Coadm with fluvoxamine (SSRI, strong CYP1A2 inhibitor): increases ramelteon levels by 70-fold.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Ramelteon - adverse effects

A

Dizziness, drowsiness, alteration of reproductive hormones

17
Q

Ramelteon - interactions

A

Alcohol, CNS depressants: potentiation of effects. Fluvoxamine: increased plasma ramelteon levels.

19 Sedative, hypnotic, anxiolytic drugs (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions