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Y4 MSK > Other Rheumatology > Flashcards

Other Rheumatology Flashcards

1
Q

What autoantibodies are associated with SLE?

A

nDNA
Sm
nRNP

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2
Q

What autoantibodies are associated with Sjogren’s syndrome?

A

Ro (anti-SSA)

La (anti - SSB)

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3
Q

What autoantibodies are associated with Polymyositis?

A

anti-Jo-1

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4
Q

What autoantibodies are associated with Subacute cutaneous lupus erythematosus?

A

RoRo (anti-SSA)

La (anti - SSB)

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5
Q

What autoantibodies are associated with systemic sclerosis?

A

anti-centromere

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6
Q

What autoantibodies are associated with CREST/limited cutaneous systemic sclerosis?

A

anti-centromere

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7
Q

What autoantibodies are associated with diffuse cutaneous systemic sclerosis?

A

anti-Sci-70

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8
Q

What autoantibodies are associated with Dermatomyositis?

A

Anti-Mi-2

ANA

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9
Q

What are the symptoms of polymyositis?

A 
•	Muscle pain, fatigue and weakness
o	Bilaterally 
o	Proximal muscles
o	Shoulder and pelvic girdle
•	Develops over weeks
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10
Q

What are the symptoms of dermatomyositis?

A
  • Gottron lesions
  • Photosensitive erythematous rash
  • Purple rash on face and eyelids
  • Periorbital oedema
  • Subcutaneous calcinosis
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11
Q

What is raised in polymyositis and dermatomyositis?

A

Creatinine kinase

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12
Q

What are the features of limited cutaneous systemic sclerosis?

A 
CREST syndrome:
•	Calcinosis
•	Raynaud’s phenomenon
•	OEsophageal dysmotility
•	Sclerodactyly
•	Telangiectasia
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13
Q

What are the features of diffuse cutaneous systemic sclerosis?

A

Features of CREST +:
• CV - HTN, CAD
• Lung - Pulmonary HTN, pulmonary fibrosis
• Kidney - Glomerulonephritis, scleroderma renal crisis

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14
Q

What are the features of Sjogren’s syndrome?

A
  • Dry mucous membranes
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15
Q

What is the characteristic features of Behcet’s syndrome?

A

Recurrent oral and genital ulcers

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Y4 MSK (11 decks)

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