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High Risk Drugs > Other Hrds > Flashcards

Other Hrds Flashcards

1
Q

Amiodarone monitoring

A

Thyroid function
Liver function
Potassium
Xray chest
Ecg

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2
Q

Amiodarone councelling

A

Sunscreen
Drivers may be dazzled by headlights at night
Ses last few months after stopping

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3
Q

Amiodarone risks

A

Thyroid symptoms
Corneal microdeposits
Sob/ cough/ dyspnoea
Lightheaded/ papitation/ chest pain/ tired
Neurological effects- tremor, peripheral neuropathy
Photosensitivity

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4
Q

Amiodarone interactions

A

Simvastatin- myopathy
Increased concentration of warfarin, dabigatran, flecainide, phenytoin
Increased arrythmia- SSRI, antipsychotics, lithium, mefloquine, tca, hydroxychloroquine
Increase bradycardia- beta blockers, diltiazem, verapamil

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5
Q

Monitoring for antipsychotics

A

Fbc
U&e
Lfts
Ecg, BP
Fbg
Lipids
Weight

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6
Q

Warning signs for antipsychotics

A

EPS
hyperthermia
Hyperglycaemia and weight gain
Hyperprolactinaemia
Labile BP and hypotension
Muscle rigidity
Dystopia, akathisia, tardiness dyskinesia
Insulin resistance
Sexual dysfunction
Arrythmka

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7
Q

Counselling for antipsychotics

A

Stay hydrated
Elderly- start at half dose
Avoid more than 1 at a time
Monitor for 2 y after withdrawal if long term
Sunscreen if high dose
Drowsiness, alcohol enhances

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8
Q

Monitoring for valproate

A

LFT
FBC
BMI
weight

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9
Q

Warnings for valproate

A

Persistent vom, abdo pain, anorexia
Jaundice, oedema, malaise, drowsy
Loss of seizure control,
Suicidal ideation
Ppp for wocbp

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10
Q

Interactions of valproate

A

Increased effects of psychotropic and warfarin
Lamotrigine metabolism Reduced
Enzyme inducing antiepileptics reduce valproate conc

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11
Q

Inadequate sun exposure with valproate

A

Offer vit d tabs

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12
Q

Monitoring with corticosteroids

A

BP
Lipids
Electrolytes
Bmi
Bone mineral density
Eye exam
Adrenal supressions signs

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13
Q

When should you take steroid

A

Am

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14
Q

Warnings in cortisteroids

A

Bronchospasm, uncontrolled asthma
Frequent antibiotics
Adrenal supression
Blurred vision
Psychiatric reactions

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15
Q

Interactions for corticosteroids

A

Metabolised faster with carbemazepine phenytoin phenobarbital rifampicin
High doses make vaccines ineffective
Masks gi effect of nsaids
Hypokalaemia with other drugs that reduce potassium

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16
Q

Sulfasalzine monitoring

A

Fbc
Renal
U&e
Lfts

17
Q

Interactions of sulfasalazine

A

Digoxin
Mercaptopurine/ azathioprine

18
Q

Warnings for sulfasalazine

A

Signs of infection
Unexplained bruising
Jaundice

19
Q

Counselling for sulfasalazine

A

Yellow orange staining- skin, soft contact lenses , urine
Maintain adequate hydration
Inhibits folic acid absorption- may cause deficiency
Caution in g6pd deficiency

High Risk Drugs (8 decks)

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