Other Blood Groups Flashcards
in the MNSsU system:
MN and Ss are found on ____
glycoproteins
in the MNSsU system:
S has a ____ on position 29 of GPB and “s’” has a____
S= methionine
s=threonine
in the MNSsU system:
Antigens are defined by ______
1st and 5th AA
which System is associated with birds?
P
In the P system:
Anti-P is an____ and ____’s complement
Anti-P1 is an ____ and ____’s complement
IgG and Activates
IgM and Binds
antigen associated with Hodgkins lymphoma
I^T
antibody associated with Mycoplasma Pneumonia
anti-I
antibody associated with Epstein Barr Virus, alcoholic cirrhosis and Myelogenous leukemia
anti-i
Tests for the P- blood group
- Anti- P1 Neutralization
- Donath-Landsteiner Test
Biggest danger is masking other Abs
I antibodies
what are the antigens in the KelL blood group system?
K,k and Js^a amd Js^b and Kp^a Kp^b
K=
k=
Kell
Cellano
Do Kell Ags denature by ficin or papain
no
what kell Ags have a high incidence?
k, Js^b Kp^b
lack Kx on RBC’s due to apparent X chromosome deletion
McClepd Phenotype
___ surpresses Kell antigens in cis postiotn
Kp*a
Usually IgG reactive in AHG phase
Need RBC or pregnancy stimulation
Low ionic strength medias may decrease activity
Albumin and PEG may enhance activity
Has been implicated in severe HTR
Associated with HDN – titer does not always accurately predict severity
Anti-K:
Are most Duffy Ags destroyed by proteolytic enzymes?
yes
what antigens are in the duffy blood group system?
Fy^a Fy^b FYFY
Well-developed at birth
Do not store well; tend to elute from RBCs
destroyed by proteolytic enxymes
Duffy Ags
; has receptor for P. knowlesi
Fy^3 antigen
appears to define receptor to which
P. Vivax enters RBCs
Fy^6 antigen
appears to be result of Fy and Rh gene
Fy5 antigen
Jka, Jkb, Jk3 (JkaJkb);
Kidd blood group
