other Flashcards

1
Q

most common cause of B12 deficiency

A

pernicious anaemia

Pernicious anaemia is the most common cause of vitamin B12 deficiency. Intrinsic factor is normally produced in the stomach and binds B12 in the gut. Autoimmune destruction of the stomach lining leads to reduced intrinsic factor production impairing B12 absorption. This can eventually precipitate a vitamin B12 deficiency and macrocytic anaemia as is the case here. B12 deficiency can also damage spinal cord myelination resulting in neurological symptoms.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

bone to prostate cancer via what plexus

A

batsons venous plexus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

bone marrow failure seen in what neuropathic pain tx drug

A

phenytoin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

isolated thrombocytopenia

A

ITP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

side effects of finateride

A

gynaecomastia and sexual dysfunction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

adrenaline induced ischaemia treated with

A

phentolamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How does finesteride shrink the prostate

A

reducing dehydrotestosterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

prothetic valves are linked to what kind of anaemia

A

haemolytic anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

universal blood donor

A

group 0

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

univresal donor for FFP

A

Group AB is the universal donor for FFP because they produce neither anti-A or anti-B and is therefore compatible with all ABO groups.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

expalin iron def an readings

A

The total iron-binding capacity (TIBC) increases as the body produces more transferrin (the iron transport protein) to maximise iron uptake

ferittin reflects stores so low
iron low to depleted stores

ransferrin saturation, which is calculated as (serum iron ÷ TIBC) × 100, will be low due to the combination of low serum iron and high TIBC.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly