OTC: General Flashcards
3 types of conjunctivitis?
Bacterial: OE then BE, Sticky purulent discharge, gritty feeling
Viral: BE due to cold/flu, Watery eyes with redness and gritty feeling - self limiting or aciclovir POM
Allergic: BE, watery, red, itchy- due to hayfever/pollen
Referral criteria for conjunctivitis?
- Closed angle closure glaucoma symptoms (n/v, blurred/hazy vision, rainbow rings, photophobia, intense eye pain and headache): can cause blindness
- Previous laser /surgery within 6 months
- Eye inflammation with rash on face
- Foreign body in the eye
- Eye/head trauma
- Keratitis (esp with contact lens)
Immediate referral in those with conjunctivitis (3)?
Glaucoma symptoms
- Sudden severe eye pain
- N/V
- Cloudy eye
- blurred/halo vision
- headache
Keratitis (corneal ulcers)
- severe eye pain, loss of vision, photophobia, redness around eyes
Uveitis
- irregular pupil shape with no response to light and photophobia
OTC treatment for conjunctivits
1) Chloramphenicol eye drops or oint: 2yrs +
2) Brolene: propamidine isoetionate
Refer if no improvement in 48hrs
Chloramphenicol eye drops dosage OTC?
1-2 drops every 2 hrs for 1st two days whilst awake
then every 4hrs next 3 days ( 5 day course)
Fridge
Chloramphenicol eye ointment dosage OTC?
TDS/QDS
Contraindications for chloramphenicol?
Myelosuppression
Blood dyscrasia
Conjunctitivits lifestyle advice?
Wash hands before and after use Dispose tissue after use Avoid sharing pillows Bathe eyelids No lens before or 24hrs after use
What causes vaginal thrush?
Candida albicans
Symptoms of vaginal thrush?
Itching and sore
Cottage-cheese like discharge (cream and curd like)
No smell
Pain during sex
Stinging skin when urinating due to scratching
OTC referral ages for thrush?
<16yrs
>60yrs
OTC failure >7days
Recurrent attacks (>2 episodes within 6 months - underlying cause)
OTC referral criteria for thrush?
<16yrs
>60yrs
OTC failure >7days
- Recurrent attacks (>2 episodes within 6 months - underlying cause)
- Smell and colour: grey, watery, fishy - BV
- Yellow/green, frothy, foul - vaginal trichomoniasis
- Vag spotting, abd. pain, dysuria - gonnorrhoea/chlamydia
- sores ulcers blisters - herpes
- STI (inform partner)
- Vaginal bleeding - cancer?
- Med ADR? antibiotics, SGLT2 inhibitors (gliflozins)
- Pregnant/diabetic/immunocompromised
Treatment options OTC for thrush?
Fluconazole 150mg STAT PO: 12-24hrs for symptom relief - treat systemically
Clotrimazole pessary/cream - internal/external (pessary at night, immediate relief)
Which OTC formulation would not be suitable for pregnant women?
Antifungal cream with applicator
Lifestyle advice for vulvovaginal thrush?
Cotton underwear Wipe front to back Avoid soap/douching Change clothes and wash after physical activity Refrain from sex due to spread moisturise with emollient
How would you treat severe infection of candidiasis?
Either two doses of oral fluconazole 150 mg (taken 3 days apart) or, if oral treatment is contraindicated, two doses of clotrimazole 500 mg vaginal pessary (used 3 days apart).
How would you treat candidiasis in pregnancy?
Intravaginal clotrimazole or miconazole should be prescribed for at least 7 days.
Oral antifungals should not be used.
What drugs can antifungals used for candidiasis interact with?
Anticoagulants like warfarin as antifungals are enzyme inhibitors CYP 3A4, CYP 2CP
Statins, CCBs, Phenytoin
Tacrolimus/Sarolimus: increased levels
What can EHC be used for?
Unprotected sex
Contraceptive failure
Advance supply e.g. going on holiday
Referral criteria for EHC?
- Severe liver impairment
- unprotected sex >5days: needs copper IUD
- Period changes: late/light/heavy
- Interacting medicines: enzyme inducers (carbamazepine, phenytoin, rifampicin, st johns wart, griseofulvin) - needs double dose but unlicensed OTC
What are the two EHC options?
Levonorgestrel - 3 days, 72hrs (16+)
Ulipristal - 5 days, 120hrs (No age)
Which EHC can you take more than once in the same cycle?
Levonorgestrel - can
Ulipristal - contra indicated
EHC should be avoided in?
Severe liver impairment
Ectopic pregnancy risk
Chrons disease
Asthma treated with steroids
Which EHC has to be stopped in breastfeeding?
Levonorgestrel OK avoid nurding 8hrs
Ulipristal - Not recommended for 1 week
Regular contraception with EHC?
Levonorgestrel - OK, start stat and barrier for 7 days
Ulipristal - use condom until next period (5days after and barrier for 2 days)
Barrier for prog - 2 days
Barrier for combined - 7 days
Advice for EHC?
Take asap.
If vomit within 3 hrs, take a double dose
Barrier method until next period
ulipristal reduced effectiveness of current contraception so use barrier methods
Abnormal bleeding at period - see gp
delayed period - see gp: levo >5days, uli >7days
Severe abdominal pain: ectopic pregnancy
Significant interactions with EHC?
Rifampicin, ciclosporin
How many missed pills of regular contraception would prompt to get EHC?
Combined: 2pills (week 1 day 1-7 EHC/week2 day 8 -14 but barriers or 3 day 15-21 no need ehc but precautions for 7 days)
Legal age of consent for sex in the UK?
16yrs, IF <16YRS: Use fraser
Offences are considered statutory rape in those under
13yrs
What is cystitis?
Infection caused by e.coli
Symptoms of cystitis?
Dysuria, haematuria, foul smell, polyuria, dark/cloudy urine
Referral criteria for cystitis?
<16, >70
Men and children
Recurrent: >2 episodes in 6 months or 3 in a year
Duration: >48hrs
Severe symptoms
Lower back/flank pain
Systemic symptoms e.g. fever, n/v (pyelo?)
Haematuria - inflammation/stones, if not painful it can be cancer
Abnormal discharge
Medication ADR: allopurinol/cyclophosphamide
Which patient groups are predisposed to UTI?
Immunocompromised
pregnant
diabetic
Treat UTI OTC?
Sodium/potassium sachets - 1 sachet TDS for 2 days - neutralises urine and provides symptomatic relief
Interaction for sodium/potassium sachets?
Contraind in hyperkalaemia/hypertension/heart disease/pregnancy/kidney disease/salt restricted diet (eg on lithium)
Interact with: ACEi, spironolactone, potassium sparing, lithium
Lifestyle advice for UTI?
lots of water pee after sex wipe front to back cranberry juice avoid douching cotton underwear
What are the OTC supply criteria for sumatriptan?
1) Must first be diagnosed by a dr or pharmacist
2) Established pattern: 5 attacks per year (approx)
3) Simple analgesia ineffective
Describe the different types of headaches
1) intense eye pain: cluster headache
2) Sinus headache: runny nose
3) aura/no aura/ n/v / unilateraly throbbing / photosensitivity / triggers- migraine
4) tight band pulsating around head - tension headache
When would you refer headache?
- OTC analgesia failure >1 day
- Oral contraceptive
- Recurring
- <12
- Severe headache >4hrs
- Trauma/injury
- inc severity and frequency
- severe deep pain when lying down
- stiff neck (meningitis)
When would you refer after that pt has been on sumatriptan?
- 1st time migraine and >50yrs
- > 4 attacks/month
- > 24hr headache
- Migraine symtpoms have changed
What conditions should sumatriptan be avoided in?
severe renal/liver impairment CVS disease (recent tia/stroke/mi) and epilepsy
Give some oTC remedies for migraine.
1) Co-codamol: max 3 days and can cause rebound headaches
2) Migraleve pink (with anti emetic buclizine)
3) Syndol: para codeine caffeine
4) n/v with migraine: buccal buccastem prochloprerazine
5) nurofen: ibuprofen
How to counsel a patient on the use of sumatriptan?
OTC: max 2 doses of 50mg and POM is max 6 x 50mg.
Take one dose stat on onset of symptoms. Then do not take another unless its for another attack. (Leave 2 hrs gap) should work within 30mins.