OT 6415 Test 1- Pre, Peri, Post Natal Flashcards
Preterm infant
Born before 38 weeks of gestation or less
- Low birthweight: 2500 grams
- Very low birthweight: 1500 grams
Postconceptual age (PCA)
- 23 weeks PCA= 5-25% survival rate
- 27 weeks PCA= >90% survival rate
Pre-Natal Genetic Disorders
-Autosomal dominant
Abnormal gene passed on from one of the non-sex chromosomes
Pre-Natal Genetic Disorders
-Autosomal recessive
Gene must be carried from both parents (1/4 chance of getting disease)
Pre-Natal Genetic Disorders
-Sex-Linked
Sex linked abnormal gene is passed on sex-linked chromosome by the mother
Pre-Natal Genetic Disorders
-Polygenetic (multifactorial)
Many genes passed from both parents
STORCH Viruses
- Syphilis
- Toxoplasmosis Can get it from changing cat litter and sand boxes or eating raw meat- fecal matter from cats can cause death, hydrocephaly, liver damage, and chorioretinits (blindness)
- Rubella (Measles)- used to be more common prior to vaccination,
- Cytomegalovirus (CMV)- type of herpes spread through the body fluids, multiple system involvement passed onto baby- Can cause multiple neurological conditions and deafness, very severe for: organ transplants, AIDs patients, and developing fetuses
- HIV/AIDS
Respiratory Problems of Prematurity
-BPD
Bronchopulmonary Disease (BPD)- acute respiratory problems that require prolonged use of ventilator -May need ECMO (Extracorporeal Membrane Oxygenation)- artificial lung oxygenates blood to circulate back to the body or a bypass
Respiratory Problems of Prematurity
-MAS
Meconium Aspiration Syndrome (MAS)- aspiration of meconium (newborn stool) into trachea and bronchi
Respiratory Problems of Prematurity
-Apnea
Prolonged pause in respiration, accompanied by slowing of the heart
Respiratory Problems of Prematurity
-RDS
Respiratory distress syndrome (RDS)- air sacs of term babies kept open by a chemical coating called surfactant for gas exchange to occur, Premature babies don’t produce this and lungs collapse
Patent Ductus Arteriosis
Premature infants: fetal circulation, which bypasses via ductus arteriosus, remains open, leading to enlargement of heart and back-up of blood in lungs
Neurological Problems of Prematurity
-Hypoxic-Ischemic Encephalopathy
Lack of oxygen due to many factors (perinatal), seizures are associated
Neurological Problems of Prematurity
-IVH
Intraventricular or Intracranial Hemorrhage (IVH)- Bleeding into cerebral ventricles and surrounding brain tissue
- Grade 1 and 2 can be reversed
- Grade 3: can cause motor problems, can cause CP. If half the tracts are affected= spastic diplegia
- Grade 4: Most severe, involves bleeding into ventricles, can cause severs CP
Neurological Problems of Prematurity
-PVL
Preventricular Leukomalacia (PVL)- necrosis of white matter below the cortex around the ventricles -type of infant brain damage