Ostomies Flashcards

1
Q

where to look for advice on if a med an be given via enteral feeding tube

A

enteral feeding tubes section in meds complete

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the main focus of pharmacy advice with peg feeding tubes

A

ensure px continue to get their meds and nutrition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

give an appropriate volume of water that can be used to flush a PEG tube before, after and in between administration of medicines

A

10ml

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what type of syringe should be used for enteral feeding

A

enteral syringes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

should drugs be mixed together for peg feeding yes or no

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

although switching to solution/ suspension ideal, tablets can be crushed and given via enteral tube when

A

if they are the only licensed product

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what class of drugs is 5fu

A

antimetabolite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

give a brief explanation of why chemotherapy is given alongside radiotherapy

A

sensitises tumour cells to radiotherapy
shrinks large tumours
helps stop spread of metastases
can be used after to kill residual cancer cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

why might patients have to wait a period of 6 weeks between completion of chemo radiotherapy and surgery

A

weakens immune system -> reduced wcc
would be at risk of thrombocytopenia and neutropenic sepsis
allows immune system to recover before surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what dietary advice can you give someone with a stoma that is experiencing constipation

A

increase fluid intake
eat wholemeal grains
brown bread and pasta
increase fruit and vegetable intake

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

who should you signpost patients with stomas to if their constipation does not resolve

A

stoma care nurse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

is constipation more common for colostomy or ileostomy

A

colostomy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what classes of medications can cause constipation

A

calcium containing antacids or opioids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

constipation can cause stoma prolapse and overflow diarrhoea, if identified who do patients need to be referred back to

A

surgical nursing support team

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

name one condition that you might wish to check in patients that have recently had a stoma relating to their mental health

A

depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

to deal with constipation you can increase faecal mass to distend the lower bowel and promote x

A

peristalsis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

list some different bulking agents that could be used to manage constipation

A

methylcellulose
isphagula husk
sterculia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

list some different osmotic laxatives that could be used to manage constipation

A

lactulose
macrogol
- retain water to inc stool volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

which type of laxative is a last resort

A

stimulant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

name 2 stimulant laxatives that could be used as a last resort for constipation in stoma patients

A

Bisacodyl
docusate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what consideration should be made to the dose of stimulant laxatives

A

smallest dose to give a soft formed stool

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

why should stimulant laxatives not routinely be given to stoma patients

A

adaptation of stoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what advice can you give to stoma patients about air travel for the first time

A

hydration
loperamide
rehydration salts
drainable and non drainable appliances
pre cut pouches
impregnanted wipes
adhesive removers
disposal bags
ensure pouch filter is working before flight

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

patients should work out how many pouches are needed for holiday and then x the number and pack some extras

A

double

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

if patients wear a closed stoma pouch why might they want to opt for a drainable one on holiday

A

in case of tummy bugs or looser stools

26
Q

why might patients want to take a travel certificate or letter explaining their condition with them

A

get through security easier

27
Q

what can be done to stoma bags if they cause ballooning due to pressure change

A

release gas or change pouch

28
Q

drug class of mesalazine

A

aminosalicylate

29
Q

how does mesalazine work to treat IBS etc

A

modulation of prostaglandin and leukotrines which are chemical mediators of inflammatory response, act locally, reduce inflammation in intestine lining

30
Q

what is the drug class of azathioprine

A

immunosuppressant

31
Q

moa of immunosuppressanst such as azathioprine

A

suppress IS, reduce inflamation, preventing rejection in organ transplantation

32
Q

azathioprine is usually titrated from what drug class

A

corticosteroids

33
Q

corticosteroids suppress leukotrines etc for crohns/UC and usually work in the first instance but eventually become

A

steroid resistant

34
Q

what monitoring is required azathioprine

A

toxicity throughout
fbc weekly first 4 weeks then every 3 months

35
Q

what are you looking for in blood tests when monitoring azathioprine

A

neutrophil and platelet depletion

36
Q

what toxicity/ warning signs are you checking for in the entirety of azathioprine therapy

A

myelosuppression

37
Q

for mesalazine renal function should be monitored how often

A

before treatment, at 3 months and then annually

38
Q

a rare issue that can occur with mesalzine use is agranulocytosis, what warning signs should you look out for

A

unexplained bruising
bleeding
tiredness
malaise

39
Q

what enzyme metabolises azathioprine

A

tpmt

40
Q

why might patients with low levels of tpmt on azathioprine need low levels of the drug compared to patients with normal enzyme levels

A

myelosuppression

41
Q

what screening can give an indication to azathioprine response but may not necessarily change treatment options and outcomes

A

tpmt

42
Q

infliximab, adalimumab and golimumab are all examples of monoclonal antibodies, how do they work

A

binds to tnf alpha to reduce inflammation and prevent damage to cells lining the gut

43
Q

what JAK inhibitor may be used to treat these conditions

A

tofacitinib

44
Q

what integrin binding drug may be used in these conditions

A

vedolizumab

45
Q

what interleukin binding drug may be used in these conditions

A

ustekinumab

46
Q

ustekinumab

A

Ulcerative colitis

47
Q

many patients dont need any pharmacological therapy after subtotal colectomy, but for those that do for rectal inflammation what may be given

A

steroid enemas or suppositories

48
Q

what food factors can aggravate stomas and cause them to become sore with more liquid output

A

beans
chocolate
spicy food
raw fruit
spinach
sweeteners

49
Q

true or false excessive consumption of beer or lager can irritate stomas

A

true

50
Q

2 drugs or classes of drugs that can cause liquid outputs and irritate stomas

A

magnesium containing antacids and methyldopa

51
Q

blockage can give symptoms of diarrhoea as solids are bypassed by liquids in the bowel, what would make you rule this out

A

extreme pain, sometimes watery output and px wont be able to stand

52
Q

what drugs should NEVER be used in the event of blockages

A

laxatives

53
Q

what drug can be used to manage diarrhoea in stomas even in high doses outside of its licence

A

loperamide

54
Q

codeine use has been associated with x in the case of ostomies

A

intestinal obstruction
so avoid long term use

55
Q

X in pouch can be used to reduce number of leaks

A

gelling agents

56
Q

what advice can you give patients to deal with pouch leakage

A

change regularly
make sure secured when exercising
gently peel barrier from skin
take time
be gentle
ensure stoma stays clean
no perfume or cream on it

57
Q

what can be used to protect broken peristomal skin

A

stoma powder

58
Q

what leakage prevention products exist

A

skin barrier rings
paste
strips

59
Q

what alternative methods of contraception may be suitable for patients aside from barrier methods

A

progesterone injections or birth control patch

60
Q

how may oral contraceptive efficacy be altered in large bowel disease

A

unlikely reduced

61
Q

how may oral contraceptive efficacy be altered in small bowel disease

A

possibly reduced
and malabsorption (crohns)

62
Q

people with autoimmune disease are more/ less at risk of VTE

A

more