Med Top Trumps Clinical Decisions Flashcards
Q1 CV
Mr Ball is a 55-year-old man with a PMH of hypertension, type 1
diabetes (ACR = 65mg/mmol) and glaucoma.
Which of the below is representative of the correct target clinic BP
target?
A.<140/90mmHg
B.<120/80mmHg
C.<150/90mmHg
D.<130/80mmHg
a <140/90mmHg
t1dm
Which of the below medications is
the MOST potent INHIBITOR of the
cytochrome P450 enzyme system?
A.Carbamazepine
B.Rifampicin
C.St Johns Wort
D.Cimetidine
d. cimetidine
are the following enzyme inducers or inhibitors
carbamazepine
st johns wort
rifampicin
inducers
enzyme inhibitors increase the effectiveness of other drugs metabolised by that enzyme thus increase or decrease the likelihood of toxicity
increase
inhibitor or inducer: cimetidine
inhibitor
inhibitor or inducer: chloramphenicol
inhibitor
inhibitor or inducer: phenobarbitone
inducer
inhibitor or inducer: phenytoin
inducer
inhibitor or inducer: fluoxetine
inhibitor
are azoles like ketoconazole and fluconazole inhibitors or inducers
inhibitors
is sodium valproate an inhibitor or an inducer
inhibitor
omeprazole and erythromycin: inducer or inhibitor
inhibitor
what would be the first line antibiotic to treat infections that care caused by staphylococcus
A.Flucloxacillin
B.Amoxicillin
C.Co-amoxiclav
D.Clindamycin
A.Flucloxacillin
give an appropriate abx that targets staphylococcus if fluclox is contraindicated due to pencillin allergy
clarithromycin
why is it best to take fluclox on an empty stomach
poor oral bioavailability
adult dose range for fluclox
250mg to 2g qds