Osteoporosis Meds Flashcards

1
Q

What do the Osteoclasts do?

A

They chew or break down the old bone cells.

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2
Q

What do the Osteoblasts do?

A

They build up new bone cells.

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3
Q

What are the causes of osteoporosis?

A
  • Lack of exercise.
  • Low Calcium diet. & Vitamin D.
  • Certain medical conditions.
  • Certain Medications (e.g Glucocorticoids)
  • Change in hormones related to bone metabolism.
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4
Q

Signs and symptoms of Osteoporosis?

A
  • Deep bone pain.
  • Pathological fractures.
  • Decreased mobility.
  • Decreased physical function.
  • Decreased muscle mass and strength.
  • Loss of height and Kyphosis (hunched back)
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5
Q

What is the diagnostic test for Osteoporosis?

A

DEXA

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6
Q

Which medications are used to treat Osteoporosis?

A
  • Bisphosphonates.
  • Estrogen.
  • Raloxifene.
  • Calcitonin.
  • Denosumab.
  • Teriparatide.
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7
Q

Example of Bisphosphonates?

A
  • They end with “dronate”
  • Alendronate
  • Ibandronate
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8
Q

Facts about Bisphosphonates?

A
  • Prescribes for Osteoporosis and Paget disease.
  • Helps prevent and treat Osteoporosis caused by long-term glucocorticoid therapy.
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9
Q

High Yield Concepts of Bisphosphonates?

A
  • Hypocalcemia.
  • Esophagitis - (Don’t lay down after taking the medications, you should move around)
  • Food interactions - (Take on a complete empty stomach, wait 30 mins before eating a meal, taken in the morning 30 mins before breakfast).
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10
Q

Examples of Vitamins & minerals?

A
  • They have names resembling the word “Calcium”.
  • Ergocalciferol (Vitamin D2)
  • Cholecalciferol (Vitamin D3)
  • Calcium
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11
Q

Facts about Vitamins & minerals?

A
  • Ergocalciferol and Cholecalciferol is prescribed for Vitamin d deficiency.
  • Calcium is prescribed for hypocalcemia, osteoporosis and muscle cramps.
  • Calcium carbonate (Tums) is used to relieve heartburn.
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12
Q

Vitamin D deficiency in children is __________?

A

Rickets

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13
Q

Vitamin D deficiency in Adults is ___________?

A

Osteomalacia

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14
Q

Calcium is important to the _____, ____ & ______?

(What kinds of system)

A
  • Nervous system.
  • Cardiac system.
  • Muscular system.
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15
Q

High Yield Concepts of Vitamins & Minerals?

A
  • Calcium - (Drink with a full glass of water to prevent kidney stones).
  • Ergocalciferol & Cholecalciferol - (Can develop toxic levels).
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16
Q

Signs of Vitamin D toxicity?

A
  • Nausea
  • Vomiting
  • Loss of appetite
  • Constipation
  • Weakness
  • Fatigue