Osteoporosis Meds Flashcards
What do the Osteoclasts do?
They chew or break down the old bone cells.
What do the Osteoblasts do?
They build up new bone cells.
What are the causes of osteoporosis?
- Lack of exercise.
- Low Calcium diet. & Vitamin D.
- Certain medical conditions.
- Certain Medications (e.g Glucocorticoids)
- Change in hormones related to bone metabolism.
Signs and symptoms of Osteoporosis?
- Deep bone pain.
- Pathological fractures.
- Decreased mobility.
- Decreased physical function.
- Decreased muscle mass and strength.
- Loss of height and Kyphosis (hunched back)
What is the diagnostic test for Osteoporosis?
DEXA
Which medications are used to treat Osteoporosis?
- Bisphosphonates.
- Estrogen.
- Raloxifene.
- Calcitonin.
- Denosumab.
- Teriparatide.
Example of Bisphosphonates?
- They end with “dronate”
- Alendronate
- Ibandronate
Facts about Bisphosphonates?
- Prescribes for Osteoporosis and Paget disease.
- Helps prevent and treat Osteoporosis caused by long-term glucocorticoid therapy.
High Yield Concepts of Bisphosphonates?
- Hypocalcemia.
- Esophagitis - (Don’t lay down after taking the medications, you should move around)
- Food interactions - (Take on a complete empty stomach, wait 30 mins before eating a meal, taken in the morning 30 mins before breakfast).
Examples of Vitamins & minerals?
- They have names resembling the word “Calcium”.
- Ergocalciferol (Vitamin D2)
- Cholecalciferol (Vitamin D3)
- Calcium
Facts about Vitamins & minerals?
- Ergocalciferol and Cholecalciferol is prescribed for Vitamin d deficiency.
- Calcium is prescribed for hypocalcemia, osteoporosis and muscle cramps.
- Calcium carbonate (Tums) is used to relieve heartburn.
Vitamin D deficiency in children is __________?
Rickets
Vitamin D deficiency in Adults is ___________?
Osteomalacia
Calcium is important to the _____, ____ & ______?
(What kinds of system)
- Nervous system.
- Cardiac system.
- Muscular system.
High Yield Concepts of Vitamins & Minerals?
- Calcium - (Drink with a full glass of water to prevent kidney stones).
- Ergocalciferol & Cholecalciferol - (Can develop toxic levels).
Signs of Vitamin D toxicity?
- Nausea
- Vomiting
- Loss of appetite
- Constipation
- Weakness
- Fatigue