Osteoporosis Flashcards
Types of Bone Cells
Osteoblasts - build bone tissue
Osteoclasts - break down bone tissue
Osteocytes - maintain bone
What decreases osteoblasts?
not enough physical activity
insufficient Vitamin K2 (M7)
low growth hormone
low estrogen
What increases osteoclasts?
low sun, dietary vitamin D low estrogen inflammation low calcium high parathyroid hormone
Digestive/Dietary Causes of Osteoporosis
- low stomach acid is associated with low calcium absorption
- excess Phosphorus - encourages calcium excretion
- excess sodium - causes calcium loss
- caffeine, sugar and alcohol - increases Ca secretion
Nutrient Deficiencies leading to Osteoporosis
- high calcium intake does not ensure strong bones and low calcium intakes do not necessarily lead to weaker bones
- Vitamin D - increase Ca absorption in the gut
- environmental toxins - fluoride, pulls calcium from bone
smoking - see radicals may affect action of osteoblasts
Reduced Estrogen & Osteoporosis
Main action of estrogen on bone is to:
- inhibit osteoclasts by increasing osteoprotegerin by osteoblasts
- inhibit production of inflammatory and bone-resorbing cytokines
Estrogen exposure decreased by: premature menopause, surgical menopause, amenorrhea, menopause
Supplements for Osteoporosis
Calcium - in a bone building formula, only if not enough from food
Vitamin D3
Magnesium - improves bone density, prevents Ca from forming insoluble deposits /stones
Vitamin K2 (MK7)
EFAs - shown to promote calcium absorption and decrease excretion, increase deposition in bone
Lifestyle Recommendations for Osteoporosis
aerobics, weight bearing exercises, stimulates bone growth
quit smoking
decrease alcohol