OSTEOPOROSIS

Question 1

A systemic skeletal disease characterized by LBD and micro architectural deterioration of bone tissue with a consequent increase in bone fragility

Answer 1

Osteoporosis

Question 2

Why does osteoporosis 3x more common in women than in men

Answer 2

Because of women having lower peak bone mass and also hormonal changes occuring at menopausal

Question 3

Causes of osteoporosis

Answer 3

Low calcium diet
Lack of physical activity
Family history
Gender
Glucocorticoids meds
Hypgonadism
Ethnicity
Excessive alcohol intake
Smoking
COPD and asthma
GI disease

Question 5

Hypogonadism

Answer 5

Low testosterone levels

Question 6

Loss of calcium by urine

Answer 6

Hypercalciuria

Question 7

Most serious osteoporotic fracture is

Answer 7

Hip fractures

Question 8

Diagnosis for osteoporosis

Answer 8

Bone mineral density

Question 9

Osteopenia

Answer 9

<2.5 SD T score

Question 10

Osteoporosis

Answer 10

greater than equal to 2.5 SD T score

Question 11

A bone density scan that is a low dose Xray which checks an area of the body such as hips, foot or hand for signs of mineral loss and bone thinning

Answer 11

Diagnosis: dual-energy x-ray absorptiometry

Question 12

A special type of spine CT that can show loss of bone mineral density, may be used in rare cases

Answer 12

Quantitative Computed Tomography

Question 13

Not very accurate in predicting osteoporosis but this may show fracture or collapse of the spinal bones

Answer 13

X-rays

Question 14

Goals of Osteoporosis Treatment

Answer 14

Control pain
Slow down or stop disease
Prevent bone fractures
Minimize risk of falls

Question 15

High calcium foods (STILLSCY)

Answer 15

Sardines
Tofu
Low fat milk
Leafy green veggies spinach and collards
Salmon
Cheece
Yogurt

Question 16

Fish oil, cod liver

Answer 16

Vit D 2217 iu

Question 17

Fish herring, Atlantic raw

Answer 17

Vit D 2061 iu

Question 18

Fish catfish, wold raw

Answer 18

Vit D 1053

Question 19

Mollusks, oyster raw

Answer 19

Vit D 941 iu

Question 20

Fish salmon, sockeye

Answer 20

Vit D 920 iu

Question 21

Fish salmon pink

Answer 21

Vit D 898 iu

Question 22

The primary drugs used to both prevent and treat osteoporosis in postmenopausal women

Answer 22

Biphosphonates

Question 23

Biphosphonates taken by mouth meds
One a week or once a month

Answer 23

Alendronate fosamax
Ibandronate boniva
Risedronate actonel

Question 24

A novel approach for the treatment of osteoporosis has just been approved by the fda

Answer 24

Reclast (zoledronic acid)

Question 25

Iv meds once a yr, —— minutes infusion

Answer 25

15

Question 26

This should be measured before each reclast dose

Answer 26

Serum creatinine (renal function)

Question 27

A medicine that slows the rate of bone loss and relieves bone pain. It comes as nasal spray or injection. Side effects nasal irritation from nasal spray and nausea when iv.

Answer 27

Calcitonin

Question 28

Less effective than biphosphonates

Answer 28

Calcitonin

Question 29

rarely used anymore to prevent osteoporosis

Answer 29

HRT or estrogens

Question 30

Approved for the treatment of postmenopausal women who have severe osteoporosis and high risk for fractures

Answer 30

Teriparatide (forteo)

Question 31

Used for prevention and treatment of osteoporosis. Similar to breast cancer drug tamoxifen. Reduce spinal fracture by almost 50%

Answer 31

Raloxifene (evista)

Question 32

Bmd should be taken at least

Answer 32

1-2 yrs

Question 33

Can be used to treat small fractures in your spinal column. Injecting fast hardening glue

Answer 33

Vertebroplasty

Question 34

Similar to vertebroplasty but here bone is drilled and a ballon tamp with contrast medium is inserted to expand then remove to create cavity

Answer 34

Kyphoplasty