Osteoporosis Flashcards
Bone cells that break down bone
Osteoclasts
Bone cells that rebuild bone
Osteoblasts
Term for bone loss
Osteopenia
Most common areas of bone loss
Lumbar spine
Hip
Distal radius (wrist)
Risk factors for osteoporosis
- Cigarette smoking
- Early menopause
- Excessive use of alcohol
- Family history
- Female gender
- Increasing age
- Decreased calcium intake
- Sedentary lifestyle/Immobility
- Thin, small frame
- White (European descent) or Asian Race
What is the name if this condition?
- Bone demineralization occurs through loss of calcium and phosphorous salts leading to fragile bones and increased risk for fracture
- Bone reabsorption accelerates, while bone formation decreases
Osteoporosis
What type of osteoporosis is this?
Occurs most often in postmenopausal women and men with low Testosterone levels
Primary
What type of osteoporosis is this?
Prolonged steroid use, thyroid-reducing medications, aluminum-containing antacids, or antiseizure medications
Secondary
All of the following are clinical manifestations of what?
“Silent Disease” because patients are usually not diagnosed until a fracture occurs after an unremarkable fall or strain
“Dowager’s Hump” – kyphosis of the dorsal spine
Loss of height (as much as 2 -3 inches)
Back pain (sharp or acute)
Pain increased with activity and relieved by rest
Restriction of movement (thoracic and lumbar regions)
Fear of falling and/or history of previous falls
Previous fractures
Constipation
Abdominal distention
Reflux esophagitis
Osteoporosis
kyphosis of the dorsal spine
Dowager’s hump
Normal T-score on a DEXA scan
-1.0 or higher
Abnormal T-score on a dexa scan
Anything below -1.0
T-Score on a DEXA scan between -1.0 and -2.5 indicates what?
Ostepenia
DEXA Scan -2.5 or lower
Osteoporosis
What type of test is this?
- Gives precise body measurements at specified skeletal points throughout the body
- Used for screening and diagnosis
- May diagnose osteopenia or osteoporosis
DEXA scan
measures volumetric bone density of spine and hip
Used for diagnostic management (to confirm diagnosis)
QCT
Normal Calcium levels
9-11
A calcium level less than 8 indicates what?
Calcium deficiency
Normal vitamin D level
- 30-50
Vitamin D level of 20-30 indicates what?
Vitamin D insufficiency
Level of vitamin D toxicity
above 50