Osteonecrosis Flashcards
1
Q
Definition
A
Death of bone and marrow as a result of poor blood supply to a region
2
Q
Pathogenesis
A
Vascular disruption due to trauma
External vascular compression due to marrow increased
Increased interosseous pressure caused by drugs
Thromboemolism
Vasculitis
Alcohol abuse
Often idiopathic
3
Q
Risk factors
A
Trauma Corticosteroids Haemaglobinopathies Hyperlipidemia Alcohol Autoimmune disease Thrombotic disorders Infection Pregnancy Haemophilia Radiation HIV
4
Q
Bones most commonly effected
A
Femoral head Femoral condyles Humeral head Proximal tibia Talus Scaphoid Lineage Navicular Lesser metatarsals Cuboid Vertebra
5
Q
Clinical features
A
Young and mobile Pain Decreased ROM 1/3 asymptomatic Often bilateral in atraumatic cases Premature degenerative disease
6
Q
Investigations
A
MRI-> decreased signal
X Ray shows late collapse
7
Q
Management
A
Avoid wt bearing
Analgesia
Bone decompression
Joint replacement