Osteonecrosis Flashcards

1
Q

Definition

A

Death of bone and marrow as a result of poor blood supply to a region

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2
Q

Pathogenesis

A

Vascular disruption due to trauma
External vascular compression due to marrow increased
Increased interosseous pressure caused by drugs
Thromboemolism
Vasculitis
Alcohol abuse
Often idiopathic

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3
Q

Risk factors

A
Trauma
Corticosteroids
Haemaglobinopathies
Hyperlipidemia
Alcohol
Autoimmune disease 
Thrombotic disorders
Infection
Pregnancy 
Haemophilia
Radiation 
HIV
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4
Q

Bones most commonly effected

A
Femoral head 
Femoral condyles
Humeral head
Proximal tibia
Talus 
Scaphoid 
Lineage
Navicular
Lesser metatarsals
Cuboid
Vertebra
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5
Q

Clinical features

A
Young and mobile
Pain
Decreased ROM
1/3 asymptomatic 
Often bilateral in atraumatic cases
Premature degenerative disease
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6
Q

Investigations

A

MRI-> decreased signal

X Ray shows late collapse

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7
Q

Management

A

Avoid wt bearing
Analgesia
Bone decompression
Joint replacement

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