Osteomalacia Flashcards
1
Q
Definition
A
Failure of bone mineralisation and accumulation of osteoid
2
Q
Risk factors
A
Vit d deficiency
Hypophosphatemia
Renal osteodystrophy
Low dietary intake and low sunlight Malabsorption Liver disease Renal disease Anticonvulsants
3
Q
Clinical features
A
Often vague Bone pain-> pelvis and long bones Fracture Skeletal deformity-> waddling gait Proximal muscle weakness
4
Q
Investigations
A
Bone profile -Ca -/increased -PO4 -/increased -ALP increased - PTH increased Decreased Vit D Normal EGFR X Ray-> losers zones -> cortical # on compression sides of bone
5
Q
Management
A
No treatment if asymptomatic
Bisphosphonates
