Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PHTH 565 - Rheumatology > Osteoarthritis > Flashcards

Osteoarthritis Flashcards

1
Q

OA is a part of normal aging (T/F)

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Like in RA, the synovial membrane is the primary site of the problem in OA (T/F).

A

FALSE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

OA (is/is not) a “wear and tear” arthritis

A

NOT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

OA is a ____ ____ disease

A

whole joint

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

4 structures involved in OA?

A
  1. cartilage
  2. synovial membrane
  3. ligaments
  4. bone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The body tries to heal the joint by laying down new bony structures, resulting in ______.

A

osteophytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

When does loss of function occur (usually) in OA?

A

End stage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

There is low grade ______ in the area of joints with OA.

A

inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Inflammatory _______ and abnormal biomechanics forces can damage cartilage.

A

enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

7 risk factors for OA?

A
  1. age
  2. sex
  3. genetic
  4. obesity
  5. physical inactivity
  6. injury
  7. joint stress
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the typical age of onset ?

A

55-60

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

OA affects more (men/women)

A

women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

It is difficult to determine the prevalence of ___ ____ OA.

A

low back

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

The prevalence of types of OA is different in different ethnicities (T/F).

A

TRUE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

There is _____ bone turnover and localized density in normal aging.

A

decreased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

There is _____ water in cartilage in normal aging.

A

decreased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

There is _______ at WB sites and it is not progressive across the joint line in normal aging.

A

fibrillation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

In normal aging, the joint has ______ metabolism and no _______.

A

normal; inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

There is a decreased in lean mm mass (type __ fibres) in normal aging.

A

II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

There is _____ bone turnover and localized density in OA.

A

increased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

There is ______ water in cartilage in OA.

A

increased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

In OA there is _____ present, both focal and progressive.

A

fibrillation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

There is ______ metabolism and _______ enzymes in OA.

A

increased; inflammatory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

There is a decrease in lean muscle mass (type __ fibres) in OA.

A

I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Knee OA is mostly _____.

A

bilateral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Is tibia-femoral or patella-femoral OA more common?

A

tibio-femoral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Is bilateral or unilateral hip OA more common?

A

unilateral

28
Q

_____ joint OA is a common type of spine OA.

A

facet

29
Q

Generalized OA = >/= to __ joints

A

3

30
Q

OA often affects ____ _____ joints.

A

weight bearing

31
Q

______ node = OA of PIP

A

Bouchard’s

32
Q

_______ node = OA of DIP

A

Heberden’s

33
Q

____ OA is a common hand OA.

A

CMC

34
Q

3 ways to classify OA?

A
  1. radiographic OA
  2. symptomatic / clinical OA
  3. MRI-defined OA
35
Q

Grading system used in radiographic OA?

A

kellgren-lawrence grading system

36
Q

Definiton used in MRI-defined OA?

A

Hunter

37
Q

4 main radiographic features of radiographic OA?

A
  1. loss of joint space
  2. osteophytes
  3. subchondral sclerosis
  4. subchondral cyst formation
38
Q

Subchondral sclerosis = increased _________ bone density

A

periarticular

39
Q

Subchondral cyst formation = typically ________ acid

A

hyaluronic

40
Q

Grade 0 kellgren-lawrence ?

A

no radiographic feautres

41
Q

Grade 1 kellgren-lawrence ?

A

doubtful

42
Q

Grade 2 kellgren-lawrence ?

A

minimal

43
Q

Grade 3 kellgren-lawrence ?

A

moderate

44
Q

Grade 4 kellgren-lawrence ?

A

severe

45
Q

4 clinical features of OA?

A
  1. pain after using joint
  2. relieved by rest
  3. morning stiffness < 30 mins
  4. stiffness after a period of inactivity
46
Q

Only __% of patients with joint damage experience pain. Why?

A

40; if it’s just affecting cartilage, won’t feel pain bc of lack of nerve supply. Pain will be experienced when soft tissue/ alignment changes occur

47
Q

Symptomatic knee OA can be dx with yes to what 4 questions?

A

Constant or intermittent discomfort or pain…

  1. at any time on most days of the month
  2. in the past year
  3. worse with activity
  4. relieved with rest
48
Q

If yes to all 4 symptomatic OA questions, move on to what 3 signs?

A
  1. effusion
  2. flexion contraction
  3. gait abnormality
49
Q

Symptomatic OA knee dx criteria?

A

yes to all 4 questions, one or more of the 3 signs present, over the age of 55

50
Q

__% of people with knee pain had MRI-detected OA that was not evident on x-rays.

A

55

51
Q

Arthritis is caused by a cold, wet climate (T/F).

A

FALSE

52
Q

_____ relieves symptoms of arthritis.

A

warmth

53
Q

Changes in ______ pressure and ambient temp may affect OA pain.

A

barometric

54
Q

3 first-line treatments of OA>

A
  1. exercise
  2. weight loss
  3. acetaminophen
55
Q

Approx __% of knee joint loading is in the medial compartment when walking.

A

70

56
Q

Knee _____ moment predicts progression of OA.

A

adduction

57
Q

High _____ strength predicts lower risk of developing OA in women.

A

quadriceps

58
Q

Quadriceps _____ is associated with knee adduction moment.

A

endurance

59
Q

Strengthening the hip _______ can reduce symptoms.

A

abductors

60
Q

______ is associated with the development of OA in knees and hips.

A

Obesity

61
Q

_______ is also linked to OA in non-weight bearing joints, such as fingers and wrists.

A

Obesity

62
Q

____ _____ _____ = associated with knee OA progression.

A

body mass index

63
Q

How to calculate BMI?

A

weight/ height^2

64
Q

To manage OA, combine ____ and ___ ___ programs.

A

exercise; weight loss

65
Q

__ lb weight loss = __ lb reduction of knee joint load per step.

A

1;4

66
Q

For pt’s with OA, general recommendation for people with OA knees and are obese is a weight loss program aimed at an initial decrease of __% body weight,

A

10

PHTH 565 - Rheumatology (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions