Osteoarthritis Flashcards
risk factors for OA
age
F>M (for hip)
obesity
trauma
joint malalignment or inflammatory condition
how can you classify OA
primary - iatrogenic / no preceeding trauma
secondary
what are some signs you may see on clinical examination for OA
muscle wasting
joint effusion
decreased ROM
what is the general pathophysiology of OA
tissue macrophages within the joint are activated and release inflammatory mediators
T helpers stimulate synovial cells to produce proteases (break down cartilage) and activated osteoclasts (create bony spurs)
what antibodies would you investigate for to support diagnosis of OA
rheumatoid factor
anti CCP
what is the escalation of pharmacalogical treatment like for OA
paracetamol
topical steroids (capsaicin)
oral NSAIDs + PPI
where are bouchards nodes found
PIPJ
associated with OA
where are heberdens nodes found
DIPJ
associated with OA