OSEO Flashcards

1
Q

epidemio del ostesacoma

A

-HOMBRES
-adultos mayores con ENF DE PAGET, INFARTOS OSEOS, RADIACION
*distribucion: 75% jovenes <20 años & 25% adultos >60 años

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2
Q

gen(es) mutados en el ostesacoma

A

!!! RB & TP53

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3
Q

CC del ostesarcoma

A

!!-masa dolorosa que aumenta de tamaño progresivamente
-fracuras sin razon aparente
!!!-RX: TRIANDULO DE CODMAN (PERIOSTIO ELEVADO), SOL NACIENTE
*localizacion mas común: rodilla o femur distal

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4
Q

macro del ostesacoma

A

-zonas de hemorragia
-infiltración a medula !!

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5
Q

micro del ostesacoma

A

!!-PROLIF DE OSTEOBLASTOS
- produccion de MATRIZ OSTEOIDE
-hueso mineralizado

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6
Q

proceso del osteocondroma

A

neoplasia benigna, origen MESENQUIMATOSA!!!

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7
Q

Epidemio del osteocondroma

A

HOMBRES JOVENES

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8
Q

cromosomas mutados en el osteocondroma

A

!!!-8, 11 & 19

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9
Q

Sd asociado al osteocondroma y cual es el gen(es) afectados

A

-Sd de exositosis familiar
-gen EXT1 Y EXT2!!

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10
Q

CC del osteocondroma

A

-Asx
*dolor si se afecta un nervio

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11
Q

macro del osteocondroma

A

lesion de ASPECTO FUNGOIDE

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12
Q

porción del hueso mas comun donde aparece el osteocondroma

A

METAFISIS

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