OSCE Stop Common S/E Flashcards

1
Q

List 4 common S/E for anti-cholinergic/muscarinic?

A

dilated pupils + blurred vision
dry mouth
constipation
urinary retention

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2
Q

List 2 common S/E for anti-histaminergic?

A

weight gain

sedation

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3
Q

Which drugs commonly cause anti-cholinergic/muscarinic S/E?

A
TCAs
Antihistamines
Hyoscine
Atropine
anti-psychotics 
PPI
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4
Q

Which drugs commonly cause anti-histaminergic S/E?

A

TCAs
anti-psychotics
anti-histamines.

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5
Q

List 3 common S/E of alpha-adrenergic block?

A

Postural hypotension
sexual dysfunction
nasal congestion

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6
Q

List 3 common anti-dopaminergic S/E?

A

EPS
hyperprolactinaemia
Neuroleptic malignant syndrome

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7
Q

Which 3 drugs commonly cause alpha-adrenergic S/E?

A

TCA
Anti-psychotics
alpha-blockers - doxazosin, tamsulosin.

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8
Q

Which 2 drugs cause anti-dopaminergic S/E?

A

Metoclopramide

anti-psychotics

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9
Q

What are the single most common side effect of the 4 TB drugs?

A

Rifampicin - red/orange tears/urine.
Isoniazid - neuropathy
Pyrazinamide - hepatitis
Ethambutol - optic neuritis.

RICE

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10
Q

What is the most important S/E of lamotrigine and how is this mitigated?

A

rash - SJS risk

very slow dose titration

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11
Q

Common S/E of SSRIs?

A

nausea, low libido, withdrawal, insomnia, GI upset initially.

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12
Q

Common S/E of TCA?

A

anti-muscarinic mostly.

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13
Q

Common S/E of MAOI

A

HHH

Hypertension
Hepatocellular jaundice
Hyperthermia

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14
Q

Common S/E of phenytoin?

A

acne
course face
gum hypertrohpy
hirsutism

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15
Q

Which 2 anti-epileptics can cause hair thinning?

A

carbamazepine

sodium valproate

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16
Q

Which 2 anti-epileptics can cause rash and SJS syndrome?

A

Lamotrigine

Carbamazepine

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17
Q

What are most common S/E of ACE-i?

A

dry cough
postural hypotension
renal failure in RAS - re-check U&E’s
angioedema

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18
Q

What are most common S/E of Ca blockers?

A

ankle oedema
headache
flushing
dizziness

19
Q

What are most common S/E of beta-blockers?

A
diabetes 
impotence
bradycardia
low exercise tolerance/fatigue 
cold extremities
20
Q

What are most common S/E of diuretics?

A

hypokalaemia (except K-sparing)
dehydration
hypotension
hypomagnesemia

21
Q

What are most common S/E of sulfasalazine?

A

discolour urine/tears (contacts).
myelosuppression
hepatitis
rash (SJS)

22
Q

What are most common S/E of MTX

A

blood - sore throat, mucositis.
liver - dark urine, pale stool, abdominal pain.
lung - SOB, chest pain

23
Q

What are most common S/E of metformin?

A

weight loss
lactic acidosis
metallic taste
GI upset

24
Q

What are most common S/E of sulphonylureas?

A

hypo

weight gain

25
Q

What are most common S/E of thiazolidinediones

A

fluid retention
hepatotoxic
bone fractures

26
Q

What are most common S/E of contraception?

A

weight gain
acne
mood changes
headaches

27
Q

What are most common S/E of clozapine?

A

agranulocytosis

monitor FBC and leukocytes regularly.

28
Q

Most common S/E for chlorpromazine?

A

cholestatic jaundice

29
Q

Most common S/E for haloperidol?

A

QT porlongation

hypotension

30
Q

What are the symptoms of lithium toxicity?

A

tremor
ataxia

coma
convulsions
hypotension

31
Q

Most common S/E for lithium?

A

nausea & diarrhoea
hypothyroidism
diabetes insipidus

32
Q

Most common S/E for steroids?

A
diabetes
Cushings 
osteoporosis
hypokalaemia
infection
33
Q

Most common S/E for L-dopa?

A
nausea
red urine
postural hypotension 
on/off effects
dyskinesias
34
Q

Most common S/E for PPI?

A

tinnitus
nausea/diarrhoea/constipation
hypomagnesaemia

35
Q

Most common S/E for amiodarone?

A
Lung - fibrosis 
Thyroid - thyroiditis 
Skin - gray, photosensitivity,
Liver - hepatitis
metallic taste
36
Q

Most common S/E for digoxin?

A

CNS - yellow/orange halo vision
GI - n+v, diarrhoea.
Cardiac - arrhythmias

37
Q

Which drugs can cause HYPERnatraemia?

A

sodium containing antibiotics, bicarbonate and fluids.

38
Q

Which drugs can cause HYPOnatraemia?

A
antidepressants 
diuretics
lithium 
chlorpromazine
carbamazepine
39
Q

Which drugs can cause HYPERkalaemia?

A

K-sparing diuretics
ACE-I
NSAIDs
trimethoprim

40
Q

Which drugs can cause HYPOnatraemia?

A

salbutamol
insulin
diuretics
caffeine

41
Q

Which drugs can cause HYPERcalcaemia?

A

thiazide diuretics

42
Q

Which drugs can cause HYPOcalcaemia?

A

Loop diuretics
bisphosphonates
phenytoin

43
Q

Which 4 C drugs can cause agranulocytosis?

A

Carbamazepine
Clozapine
Colchicine
Carbimazole

44
Q

Which 4C drugs can cause C.diff?

A

Cephalosporins
Co-amox
Clindamycin
Ciprofloxacin