Orthopaedics and Rheumatology Flashcards
Urethritis, conjunctivitis, arthritis
Associated lesions include circinate balanitis
Keratoderma blenorrhagica
Mouth ulcers
Previous STI or gastroenteritis
Reiter’s syndrome
Young male, buttock/sacroiliac pain worse in morning, relieved by exercise Syndesmophytes, ‘bamboo spine’ on X-ray
Associations include 4 As: arthritis, anterior uveitis, apical lung fibrosis, aortic regurgitation
Ankylosing spondylitis
Nail dystrophy, ‘pitting’
Joints show central erosion on X-ray
Can be highly deforming (arthritis mutilans)
Psoriatic arthritis
Arthritis in UC/Crohn’s patient
Asymmetrical, mainly affects lower limbs
Enteropathic arthropathy
Dry eyes, dry mouth
Positive Schirmer’s test
Sjögren’s syndrome
Proximal muscle weakness, pain and tenderness
Increased serum CK
Polymyositis
Proximal muscle weakness, pain and tenderness
Increased serum CK
Heliotrope (purple) rash
Dermatomyositis
More common in Turkish, Iranian patients
Orogenital ulceration, uveitis, arthritis
Pathergy reaction is pathognomonic
Behçet’s disease
Usually woman
Persistently cold, cyanosed fingers
Raynaud’s phenomenon
Calcinosis (nodules)
Raynaud’s phenomenon
Esophageal dysmotility
Sclerodactyly
Telangiectasia
CREST
Systemic sclerosis
Usually elderly patient with headache
Scalp tenderness
Jaw claudication
Sudden unilateral blindness can occur
Associated with polymyalgia rheumatica
Temporal/giant cell arteritis
Granulomas in respiratory tract
Generalised vasculitis
cANCA, anti-PR3 positive
Wegener’s granulomatosis
Usually child (particularly under age 5)
Purpuric rash over buttocks, extensor surfaces
Associated with arthritis, abdominal pain and nephritis
Henoch-Schönlein purpura
Usually middle-aged male
Asthma, rhinitis and systemic vasculitis
+++ eosinophilia
Churg-Strauss syndrome
Usually under 5 years
Main features are:
- protracted fever
- acute cervical lymphadenopathy
- bilateral non-purulent conjunctivitis
- dry, cracked, fissured lips
- redness, oedema of palms and soles
Platelets and CRP usually elevated
Kawasaki’s disease
Anti double-stranded DNA
SLE
Anti-Jo-1 antibodies
Polymyositis
Anti-centromere
Limited systemic sclerosis
Anti-topoisomerase
Diffuse systemic slcerosis
cANCA, anti-PR3
Wegener’s granulomatosis
α-endomysial antibody
Coeliac disease
Anti-cyclic citrullinated peptide antibody
Rheumatoid arthritis
Radiological findings
- Loss of joint space
- Subchondral sclerosis
- Subchondral cysts
- Osteophytes
Osteoarthritis
Radiological findings
- Loss of joint space
- Juxta-articular osteoporosis
- Erosions
- Subluxation joints
Rheumatoid arthritis
Radiological findings
- Localised enlargement of bone with deformity (e.g. enlarged skull, bowed tibia)
Paget’s disease
Radiological findings
- Syndesmophytes
- ‘Bamboo-spine’ appearance
Ankylosing spondylitis
‘Sunray’ spiculation
Osteosarcoma
‘Onion-peel sign’
Ewing’s sarcoma
Thickening, fibrosis palmar fascia
Dupuytren’s contracture
Forced adduction and flexion thumb elicits pain on radial side wrist
De Quervain’s syndrome