orthopaedic oncology Flashcards

1
Q

what does osteo mean

A

bone

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2
Q

what does chondro mean

A

cartilage

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3
Q

what does scaro mean

A

soft tissue

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4
Q

how many groups can bone tumours be separated into

A

3

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5
Q

what groups can bone tumours be separated into

A

bone forming (osteo), cartilage forming (chondro), others (usually causing bone destruction)

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6
Q

what are risk factors for primary bone cancers

A

mostly idiopathic, previous radiotherapy, conditions (pagets, fibrous dysplasia, multiple enchondromas), genetic

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7
Q

what are presenting features of bone cancers

A

persistent increasing pain (well localised), usually not associated with movement, worse at night, doesn’t respond well with normal analgesia, palpable mass, pathological fracture

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8
Q

what group is bone cancer more suspected in

A

young patients aged 10-30

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9
Q

what are diagnostic tests associated with bone cancer

A

plain radiographs (AP and lateral including joint above and below), CT, MRI, bone scan

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10
Q

what is true of X-rays and bone cancer

A

it may not show up on X-rays until over 50% of cortical bone is lost so need more detailed imaging ig clinical suspicion

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11
Q

what is true in bone scans

A

bone turn over can also be increased in infection or arthritis

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12
Q

what is treatment for bone cancer?

A

neoadjuvant (chemo/radiotherapy/hormone to shrink cancer or reduce metastases before surgery), surgery (reconstructive or amputation), adjuvant (chemo/radiotherapy)

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13
Q

what is an osteosarcoma

A

formation of abnormal bone

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14
Q

what is seen on X-ray of osteosarcoma

A

increased whiteness

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15
Q

what is the most common sarcoma of bone

A

osteosarcoma

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16
Q

what age group is most commonly affected by osteosarcoma

A

10-30’s, second peak in elderly (pagets)

17
Q

where is osteosarcoma commonly found

A

around distal femur/proximal tibia (around knee)

18
Q

how many osteosarcomas present with pulmonary metastases?

A

10-20%

19
Q

what is the long term survival rates of an osteosarcoma

A

75%