ORGANIZATION THAT CLASSIFY ANEMIA Flashcards
First system, still used by some but being replaced by WHO
Classified acute leukemia as presence of ≥30 % blast in the peripheral blood and bone marrow
a. FRENCH AMERICAN BRITISH (FAB)
b. WORLD HEALTH ORGANIZATION
a. FRENCH AMERICAN BRITISH (FAB)
Widely used to classify leukemia. It is now the
standard classification in diagnosing leukemia
WHO defines acute leukemia as ≥ 20%
peripheral blood and bone marrow
blasts.
a. FRENCH AMERICAN BRITISH (FAB)
b. WORLD HEALTH ORGANIZATION
b. WORLD HEALTH ORGANIZATION
Subdivide leukemia according to:
1. Cellular morphology
2. Cytochemical staining results.
a. FRENCH AMERICAN BRITISH (FAB)
b. WORLD HEALTH ORGANIZATION
a. FRENCH AMERICAN BRITISH (FAB)
Subdivide leukemia according to:
- Cellular morphology
- Cytochemical stains (cytochemistry)
- Immunophenotyping (Flow cytometry)
- Cytogenetics abnormalities
- Clinical syndrome.
a. FRENCH AMERICAN BRITISH (FAB)
b. WORLD HEALTH ORGANIZATION
b. WORLD HEALTH ORGANIZATION
Devoted to the laboratory study of visible chromosome abnormalities, such as deletions, translocations, and aneuploidy
A.Immunopheno- typing
(Flow cytometry)
B.Cytochemistry
C. Cytogenic (Karyotyping Analysis)
C. Cytogenic (Karyotyping Analysis)
Use of specialized stains to detect cellular enzymes and other chemicals in peripheral blood films and bone marrow aspirate smears. Used to differentiate hematologic diseases, especially leukemias.
A.Immunopheno- typing
(Flow cytometry)
B.Cytochemistry
C. Cytogenic (Karyotyping Analysis)
B.Cytochemistry
Used to identify cells on the basis of the types of markers or antigens present on the cell’s surface, nucleus, or cytoplasm. This technique helps identify the lineage of cells using antibodies that detect markers or antigens on the
cells
A.Immunopheno- typing
(Flow cytometry)
B.Cytochemistry
C. Cytogenic (Karyotyping Analysis)
A.Immunopheno- typing
(Flow cytometry)
