4 MAJOR TYPES OF LEUKEMIA

Question 1

is the most common type of leukemia in adult, and the incidence increases with age.
a. Chronic Lymphocytic
leukemia (CLL)
b. Acute myeloid leukemia
(AML)
c. Acute lymphoblastic
leukemia (ALL)

Answer 1

b. Acute myeloid leukemia
(AML)

Question 2

Primarily a disease of childhood and adolescent, accounting for 25% of childhood cancers and up to 75% of childhood leukemia

a. Chronic Lymphocytic
leukemia (CLL)
b. Acute myeloid leukemia
(AML)
c. Acute lymphoblastic
leukemia (ALL)

Answer 2

c. Acute lymphoblastic
leukemia (ALL)

Question 3

-Early pre-B cell or common ALL (60-70%)

-T cell ALL (10-20%) - associated with large mass in the mediastinum

-B cell ALL (RARE)

a. Chronic Lymphocytic
leukemia (CLL)
b. Acute myeloid leukemia
(AML)
c. Acute lymphoblastic
leukemia (ALL)

Answer 3

c. Acute lymphoblastic
leukemia (ALL)

Question 4

appears to involve B lymphocytes, occurring
more in man than in women

Clinical signs are lymphadenopathy, fatigue, weight loss,
splenomegaly, and hepatomegaly

a. Chronic Lymphocytic
leukemia (CLL)
b. Acute myeloid leukemia
(AML)
c. Acute lymphoblastic
leukemia (ALL)

Answer 4

a. Chronic Lymphocytic
leukemia (CLL)

Question 5

Common abnormalities:

1.** Uric acid- **hyperuricemia
2. **Electrolytes affected **= Calcium, potassium, and phosphate

a. Chronic Lymphocytic
leukemia (CLL)
b. Acute myeloid leukemia
(AML)
c. Acute lymphoblastic
leukemia (ALL)

Answer 5

b. Acute myeloid leukemia
(AML)

Question 6

Lymphocytes are fragile

Large number of smudge cells are present

a. Chronic Lymphocytic
leukemia (CLL)
b. Acute myeloid leukemia
(AML)
c. Acute lymphoblastic
leukemia (ALL)

Answer 6

a. Chronic Lymphocytic
leukemia (CLL)

Question 7

Bone marrow and peripheral blood films show small lymphoid
cells with a characteristically coarse chromatin(“soccer-ball” pattern), absent or inconspicuous nucleoli, and scant cytoplasm

a. Chronic Lymphocytic
leukemia (CLL)
b. Acute myeloid leukemia
(AML)
c. Acute lymphoblastic
leukemia (ALL)

Answer 7

a. Chronic Lymphocytic
leukemia (CLL)

Question 8

A myeloproliferative disorder characterized by pancocytosis

▪ 90% of cases are positive for Philadelphia chromosome t(9:22)

a. Chronic Lymphocytic
leukemia (CLL)
b. Acute myeloid leukemia
(AML)
c. Acute lymphoblastic
leukemia (ALL)
D. Chronic Myelogenous
Leukemia (CML)

Answer 8

D. Chronic Myelogenous
Leukemia (CML)