Organic Synthesis

Question 1

Overview of additional functional groups and their properties

Answer 1

Question 2

Reactions by which functional groups can be produced

1. benzoic acid
2. acyl chloride
3. Amide

Answer 2

Question 3

Reactions by which functional groups can be produced

1. Arene
   
   1. Halogenation
   2. Nitration
   3. Friedel-Crafts Alkylation

Answer 3

Question 4

Reactions by which functional groups can be produced

1. Arene
   
   1. Friedel-crafts acylation
   2. complete oxidation
   3. hyrdogenation

Answer 4

Question 5

Reactions by which functional groups can be produced

1. Phenol
   
   1. Esterfication
   2. Acid/Base (basic)
   3. Acid/Base (acidic)

Answer 5

Question 6

Reactions by which functional groups can be produced

1. Phenol
   
   1. Nitration
   2. Bromination

Answer 6

Question 7

Multi-Step Synthetic Routes

Answer 7

• Many organic molecules are made in multi-step synthetic routes
• Students should be able to recall the different reactions each functional group undergoes and apply this knowledge when devising multi-step synthetic routes for preparing organic molecules

Question 8

Analysis of Synthetic Routes

Answer 8

• Students should be able to apply their knowledge on functional groups and their reactions by critically analysing a given synthetic route in terms of:
  
  • The type of reaction
  • The reagents used for each step
  • Any possible by-products