Organic II Practice Exam + Quizzes Flashcards
What is the driving force for losing a Proton as the last step in the electrophilic aromatic substitution?
To rearomatize the ring system.
List 3 things about the Friedel-Crafts Alkylation.
Reaction fails when strongly deactivating substituent is present.
Rearrangement is possible.
Multiple alkylations frequently occur.
1° alcohol reacting with K2Cr2O7, H2SO4 and H20 produces what?
Carboxylic acid.
What 2 different reagents reacting with 1° alcohol produces a ketone
PCC
K2Cr2O7, H2SO4, H20
Triple bonded N reacting with what produces an aldehyde?
DIBALor LiAlH4
DIBAL can ______ ketone and aldehydes to __________.
reduce; alcohol
Why are alkylamines more basic than arylamines?
The lone pair electrons are localized in alkylamines and delocalized in arylamines.
NH2 group reacting with 1. CH3I 2. Ag2O, H2O 3. Heat changes to what?
An alkene (less substituted; Hofmann)
What reagent changes aniline to N triple bonded to N?
NaNO2 and HCl
In electrophilic aromatic substitution, the attacking species (the electrophile) necessarily is a
lewis acid
What reagent changes a primary alcohol to a carboxylic acid?
Kr2Cr2O7, H2SO4, H2O
What is the difference between phenyl and benzyl?
Phenyl: Benzene ring
Benzyl Benzene ring with CH2-R
What is the hydrazone group?
R=N-NH2
What does Sia2BH/THF and H2O2, OH- do to a C triple bonded to CH?
Change to aldehyde CHO
A weak C.A have a _____ pKa and is a ______ base.
high; strong
