Organic Disorders Flashcards

1
Q

What an organic brain disorder?

A

Mental disorder due to common, demonstrable cause of cerebral disease, brain injury or other insult
Either primary or secondary

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2
Q

What are the clusters of symptoms of organic brain disease?

A
Cognitive (memory, intellect0
Sensorium (consciousness, attention)
Mood
Psychosis
Later onset, progressive
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3
Q

What are the different types of organic mental disorders?

A
Acute/subacute 
 - Delirium
 - Organic mood/psychosis disorder
Chronic 
 - Dementia
 - Amnesiac syndrome
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4
Q

How is Delirium characterised?

A

Concurrent disturbances of consciousness, perception, thinking, memory, psychomotor, emotion

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5
Q

What are the presenting features of delirium?

A
  1. Impairment of consciousness and attention
  2. Global disturbance of cognition
  3. Psychomotor disturbances
  4. Disturbance of sleep-wake cycle
  5. Emotional disturbance

Rapid onset with diurnal fluctuation, <6 months

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6
Q

How is delirium managed?

A
Treat underlying cause
Supportive measures:
 - Safe environment
 - Optimise stimulation
 - Educate relatives, med staff
Correct contributing factors
Avoid sedation
Antipsychotics, Benzos, Promethazine
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7
Q

What is the medical management of delirium?

A

AVOID sedation
Benzos
Antipsychotics
Promethazine

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8
Q

How does Hepatic Encephalopathy present?

A
General psychomotor retardation
Drowsiness
Fluctuating confusion
Asterixis
(Build up of toxic products - ammonia)
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9
Q

How does Amnesic syndrome present?

A
Impairment of recent and remote memory
Immediate recall preserved
New learning reduced
Anterograde amnesia
Disorientation in time
Retrograde amnesia 
Confabulation
Perception and other cognitive functions preserved
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10
Q

What are the main types of Amnesic syndrome?

A

Diencephalic damage

Hippocampal damage

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11
Q

What causes Diencephalic Amnesic syndrome?

A

Korsakoff’s syndrome
3rd ventricle tumours
Bilateral thalamic infarction

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12
Q

What causes Hippocampal Amnesic syndrome?

A

HSV encephalitis
Anoxia
Head injury
Early alzheimers

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13
Q

What is the management of amnesic syndrome?

A

Fix cause

Thiamine in alcoholism

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