Organelles Flashcards
Nucleus
- Contains most genes of the cell
- Contains nucleolus
- Membrane bound organelle (nuclear envelope: phospholipid bilayer)
- Helps direct protein synthesis (synthesis of mRNA)
Functions of nucleus
- Control cellular structure/ activities
- site of DNA replication/ mRNA production
- Produces ribosomes (nucleolus)
Nuclear envelope
- Double membrane (lipid bilayer with an inner & outer membrane)
- Contains pores (due to fusion of 2 membranes /To regulate entry & exit of the cell)
- On nuclear side: Nuclear lamina (network of proteins that help maintain the shape of the nucleus)
Function of nuclear membrane
Separate nucleus from cytoplasm
Nucleolus
Site of rRNA synthesis
- Assembles rRNA + proteins into ribosomal subunits (large & small)
Function of Ribosomes
Site of protein synthesis
Ribosomes
- Made rRNA + proteins
- Composed of 2 subunits
- 2 types:
Free; - in cytosol
- make proteins functionning in cytosol
Bound; - attached to endoplasmic reticulum or nuclear envelope
- make proteins for membranes (aquaporin) and for secretion (insulin)
Endomembrane system
Transport system of proteins - Nuclear envelope - Endoplasmic reticulum - Golgi apparatus - Vacuoles - Lysosomes - Plasma membrane connected directly through physical contact (Nucleus-ER) or indirectly by transport vesicles
Smooth ER
lacks ribosomes
- Synthesizes lipids (like hormones)
- Metabolizes carbohydrates
- Detoxifies drugs and poisons (liver)
- Stores calcium ions (muscle)
Rough ER
attached to ribosomes
- membrane production (membrane bound proteins)
- protein synthesis (secretory proteins; glycoprotein)
- Distributes transport vesicle (protein surrounded by membranes)
Endoplasmic Reticulum
- Network of tubules and sacs (cisternae)
- continuous with nuclear envelope
- 2 regions : Rough & smooth
Golgi apparatus
- flattened membranous sacs = cisternae
- contains cis (receiving) and trans (shipping) sides
Functions of Golgi Apparatus
- Modifies, sorts and packages glycoproteins from rough ER
- Receives vesicles from rough ER (cis)
- Ships vesicle to other end (trans)
- Produces polysaccharides
- Makes lysosomes
Lysosomes
- Membrane enclosed sacs of hydrolytic enzymes
- has an acidic environment (pH=5)
- enzymes (proteins) synthesized in RER; processed by Golgi
Functions of Lysosomes
1) Intracellular digestion:
- Lyosomes fuse with food vacuole produced by phagocytosis (cell engulating another cell or food particle)
2) Recycles old/damaged organelles:
- called autophagy
- components released into cytosol for re-use
Vacuoles
- membrane bound sacs
- perform different functions in different cels
Food vacuoles
formed by phagocytosis
Contractile vacuole
pumps excess of water out of cells (paramecium)