Organ dysfunction Flashcards

1
Q

The use of mechanical ventilation?

A
  • Reduce work of breathing
  • Support gas exchange
  • Buy time for other interventions
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2
Q

What is Type 1 respiratory failure?

A

PO2 < 8

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3
Q

What are the causes of type 1 respiratory failure?

A
  • V/Q mismatch
  • Shunt
  • Hypoventilation
  • Impaired diffusion
  • Low inspired fraction of oxygen
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4
Q

What is type 2 respiratory failure?

A

CO > 6 and PO2 < 8

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5
Q

Whats are the causes of type 2 respiratory failure/

A
  • increased co2 production
  • Decreased co2 elimination
  • Decreased CNS drive
  • Neuromuscular disease
  • Increased work of breathing
  • Asthma/COPD
  • Pulmonary fibrosis
  • Kyphoscoliosis
  • Increaeed physiological dead space - Hypovolaemia, low CO, alveolar overdistention
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6
Q

What is type 3 respiratory failure?

A
  • Perioperative
  • Atelectasis
  • Low FRC
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7
Q

what is type 4 respiratory failure?

A
  • Shock
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8
Q

Components of the berlin criteria for ARDS

A
  • Within one week of known clinical insult
  • Bilateral opacities - No explained by effusions
  • Not explained by cardiac or fluid overload
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9
Q

Levels of PaO2/FiO2 ratio on PEEP of 5?

A
  • Mild = 200-300 mmHg
  • Moderate = 100 - 200 mmHg
  • Severe = < 100 mmHg
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10
Q

What is the normal peak inspiratory flow?

A

20-30L/min

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11
Q

What is the PEEP effect of optiflow?

A

Approximately 1 cmH20 / 10L/min of flow

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12
Q

Typical patients requiring NIV?

A
  • COPD / Type 2 RF
  • Pulmonary oedema
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13
Q

Mechanics of CPAP in cardiogenic pulmonary oedema?

A

Reduced LV after-load via positive intra-thoracic pressure

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14
Q

What is the normal value of respiratory compliance ?

A

> 50ml/cmH2O

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15
Q

What are the effects of PEEP on venous return?

A

Reduction with hypotension

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16
Q

What are the effects of PEEP on PVR?

A
  • Compression of pulmonary capillaries
  • Increased RV afterload
  • Reduction of stroke volume
17
Q

What are the effects of PEEP on LV ?

A
  • LV afterload is reduced
18
Q

What is the definition of LV afterload ?

A

SBP - Intrathoracic pressure

19
Q

How is airway resistance derived?

A

The difference between Pplat - PIP

20
Q

What is driving pressure?

A

This is the pressure required to distend the respiratory system