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SPDX311 > organ donation > Flashcards

organ donation Flashcards

1
Q

identifies opportunities to
assess the risks for common post-transplant infections and to develop individualized preventative strategies.

A

pretransplant evaluation

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2
Q

therapy of choice
for a variety of types of organ failure

A

solid organs transplantation

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3
Q

two major complications of organ transplantation

A

infection and malignancy

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4
Q

conditions which may disqualify either
donor or recipient

A

Hepatitis C virus (HCV) and HIV

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5
Q

two types of serologic
tests for syphilis

A

non-treponemal
tests and treponemal-specific
tests

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6
Q

detect antibodies against cardiolipin and
are not specific

A

non-treponemal test

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7
Q

detect antibodies against specific
treponemal antigens

A

treponemal test

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8
Q

CDC recommends this test which is superior specificity and sensitivity compared with
the fluorescent treponemal
antibody absorption assay.

A

Treponema pallidum - particle agglutination assay

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9
Q

The two methods to assess
cellular immune response

A

in vivo tuberculin skin test
(TST) and ex vivo interferon
gamma release assays (IGRA).

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10
Q

elicits a delayed–type
hypersensitivity reaction after
local intradermal application of
purified protein derivative.

A

tuberculin skin test

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11
Q

diameter of induration after inoculation

A

greater than or equal to 5
millimeter measure 48-72 hours

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12
Q

greater than or equal to 5
millimeter measure 48-72 hours is considered as

A

positive result in HIV, recent contacts to
infection TB, and
immunocompromised host

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13
Q

diameter of induration of individuals with any TB risk factors

A

10-15 mm

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14
Q

Two methods of quantifying GRA
production

A

enzyme link
immune assay and enzyme link
immunospot assay

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15
Q

if the measure excessed
a specific threshold relative to the
control. Should undergo a
thorough evaluation to rule out
active infection. Treated if there
is no evidence of active TB infection

A

Positive result

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16
Q

Transplant recipients are _______ are more likely to harbour
TB than the general population

A

20-74 times

17
Q

commonly accepted indirect
measure of latent infection

A

Detecting the cellular response
against TB specific antigen

18
Q

Transplant recipients are at risk for several parasitic infections including

A
  • toxoplasmosis
  • strongyloidiasis
19
Q

uncommon
but highly morbid infection after
transplantation

A

toxoplasmosis

20
Q

toxoplasmosis test involves detection of

A

IgG antibodies

21
Q

devastating
disease in transplant recipients,
with 50–70% mortality in those
with hyperinfection syndrome
and disseminated infection.

A

strongyloidiasis

22
Q

what is the test for strongyloidiasis

A

serial stool ova
parasite examinations
ELISA

23
Q

result from
primary infection reactivation of
latent infection or donor derived
infection

A

posttransplant

24
Q

has the
highest sensitivity and involves
inoculating an agar plate with
stool sample and incubating it
for atleast 2 days.

A

agar plate method

25
Q

False positive in ELISA

A

results of cross reactivity
with other helminths infections

26
Q

Immunologic and virologic control must be
documented prior to transplantation.

A

HIV

27
Q

responsible for coordination of the evaluation and preparation of patients for organ transplantation and long-term management of patients after transplant

A

Transplant Coordinator

28
Q

Major Responsibilities

A

Direct Patient Care
Program Development
Research
Education
Consultation

29
Q

Develop and present information to professional
groups regarding organ transplantation and organ
donation.

A

education

30
Q

Participate in the development and implementation
of research protocols and interpret the protocols
for Participation of patient and family members

A

research

31
Q

Collaborate in the development of protocols and
guidelines for patient management

A

Program Development

32
Q

Develop, implement and evaluate comprehensive
patient education programs

A

Program Development

33
Q

Support planning of and participate in clinical
research projects

A

research

34
Q

Develop and present information to community
groups regarding organ transplantation and organ
donation

A

education

35
Q

Participate in the development of marketing
information regarding organ transplantation and
organ donation.

A

education

SPDX311 (10 decks)

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