Orbitofrontal

Question 1

ALL IMPORTANT

What role does the orbitofrontal cortex (OFC) play?

Answer 1

Emotion regulation, response inhibition, and social behaviors

The OFC is critical in managing how we respond to emotional stimuli and social interactions.

Question 2

What can damage to the orbitofrontal cortex (OFC) cause?

Answer 2

Impulsivity, social inappropriateness, lack of empathy, aggressive behaviors, and emotion dysregulation

Examples of social inappropriateness include immature behavior, inappropriate jocularity, and inappropriate disclosure of personal information.

Question 3

Which psychiatric disorders are linked to abnormalities in the orbitofrontal cortex (OFC)?

Answer 3

• Major depressive disorder
• Bipolar disorder
• Obsessive-compulsive disorder
• PTSD
• Schizophrenia
• Substance use disorders

These disorders may involve dysfunctions in the OFC, reflecting its importance in mental health.