Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Oral Medicine- Cancer > Oral Potentially Malignant Disorders > Flashcards

Oral Potentially Malignant Disorders Flashcards

1
Q

Orally Potentially Malignant Disorders: Before describing something as leukoplakia, what three things need to be excluded?

A
  1. Trauma
  2. Immune-mediated
  3. Infections
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Orally Potentially Malignant Disorders:

True or False: Proliferative Verrucous Leukoplakia is a rare, aggressive subset of OPMD

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Orally Potentially Malignant Disorders: Proliferative Verrucous Leukoplakia is more of less resistant to treatment

A

More

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Orally Potentially Malignant Disorders: Proliferative Verrucous Leukoplakia is a _____ potential for malignant transformation

A

Strong

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Orally Potentially Malignant Disorders: What are the four phases of Proliferative Verrucous Leukoplakia?

A
  1. Focal early presentation
  2. Geographic expansion with time
  3. Development of verrucoid/warty appearance
  4. Development of cancer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Orally Potentially Malignant Disorders: What is the most common site for proliferative verrucous leukoplakia?

A

Gingiva

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Orally Potentially Malignant Disorders: Describe the progression of epithelial dysplasia to malignant transformation

A

Normal stratified squamous histology -> epithelial dysplasia -> Invasive SCC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Orally Potentially Malignant Disorders: Malignant transformation risk factors

A

Long duration, female gender, location, dysplasia, leukoplakia present in non=smoker, size

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Orally Potentially Malignant Disorders:

Five molecular predictors

A
  1. E-cadherin expression
  2. LOH 3P and 9P
  3. P53 expression
  4. P16 expression
  5. ERK/MAP alterations
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Orally Potentially Malignant Disorders: Describe Mild (Low Grade) Epithelial Dyplasia

A

Hyperchromatic and slightly pleomorphic nuclei localized to the basal and parabasilar areas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Orally Potentially Malignant Disorders: Describe moderate (medium grade) epithelial dysplasia

A

Dysplastic features extending from the basal layer to the midportion of the spinous layer. Characterized by nuclear hyperchromatism, pleomorphism and cellular crowding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Orally Potentially Malignant Disorders: Severe (high grade) epithelial dysplasia

A

Dysplasia extends from the basal layer to beyond the midpoint of the epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Orally Potentially Malignant Disorders: If a white patch is diagnosed clinically as leukoplakia, should we biopsy?

A

MUST biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Orally Potentially Malignant Disorders: Treatment for Moderate Dysplasia

A

Surgical Removal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Orally Potentially Malignant Disorders: Treatment for Severe Dysplasia

A

Surgical Removal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Orally Potentially Malignant Disorders: Treatment for Carcinoma in situ

A

Surgical Removal

Oral Medicine- Cancer (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions